195 resultados para biología
Resumo:
332 p. : il., gráf.
Resumo:
The study is focused on structural aspects of interaction between silencing suppressor p19 and CUG-repeating small RNAs. The work involves crystal structure determination of a protein-unbound RNA form and RNA fragments of various lengths (19, 20, 21 nucleotides) complexed with p19-suppressor. Results prove the ability of silencing suppressor p19 to bind CUG-repeating small RNAs, as well as reveal features of U•U mismatches flanked by Watson-Crick C•G base pairs in p19-bound and p19-unbound states. In addition, structural data reveal a p19 specific site for anchoring extra nucleotides in small RNAs. In general, the study extends our knowledge about the mechanism of small RNA recognition by silencing suppressor p19.
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222 p. : il.
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399 p. : il., graf.
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220 p.
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228 p.
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228 p. : il. Nota: Otro título en Teseo: "la modulación selectiva de los niveles de glutatión con l-2-oxo-4-tiazolidina carboxilato aumenta la eficacia de la interleucina-2 e incrementa el beneficio terapéutico de la bioquimioterapia del melanoma metastático"
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333 p.
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224 p.
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188 p.
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198 p.
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182 p.
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251 p. : il., col.
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340 p.
Resumo:
239 p.: il.-- [Editores del libro: Genaro Guisasola y Mikel Garmendia]