Láser Q-Switched en el manejo de ocronosis exógena: revisión sistemática de la literatura


Autoria(s): Perico Hurtado, Viviana Andrea; Cadena Vanegas, Diana Lucia
Contribuinte(s)

Bernal, Claudia Alicia

Barragan, Ana M.

Data(s)

28/07/2016

Resumo

Antecedentes: La ocronosis Exógena (OE) es una enfermedad subdiagnosticada y de difícil manejo (1). El láser Q-Switched (QS) surge como una alternativa para el tratamiento de esta (2). Objetivo: Describir las características de los pacientes, del láser QS y los desenlaces en el tratamiento de OE. Métodos: Se realizó una búsqueda de la literatura en las bases PubMed, Embase, PMC, Scielo, Elselvier, BMJ Case Reports, Journal of Medical Case Reports, Cases Journal e International Medical Case Reports Journal, desde enero del 2000 a marzo del 2016, pacientes con ocronosis exógena, 18 a 70 años, tratados con láser QS. Los artículos fueron evaluados mediante la herramienta de evaluación de validez y valor educativo de reportes de caso descrito por Pierson (3). Resultados: Se encontraron 256 artículos, 63 fueron seleccionados: 28 repetidos y 31 no cumplieron criterios de inclusión. Se escogieron 4 artículos que reportan 12 casos de pacientes con ocronosis exógena diagnosticada mediante estudio histopatológico y tratada con láser QS. Discusión: Hay poca experiencia con el láser QS en OE. En la práctica clínica se usa para tatuajes y patologías pigmentarias dérmicas con resultados satisfactorios. El pigmento dérmico en OE y la corta duración de pulso de láser QS, podrían ser el pilar de tratamiento para OE. Conclusión: El láser QS puede ser útil para el tratamiento en OE, con nivel de evidencia 3 y grado de recomendación D. Se sugiere realizar estudios clínicos con mayor grado de evidencia.

Background: Exogenous Ochronosis (OE) is an underdiagnosed and difficult to treat condition (1). The Q-switched (QS) laser is an alternative for the treatment of this disease (2). Objective: To describe the patient’s characteristics and the QS laser features and subsequent outcomes after the use of this type of laser in the treatment of exogenous ochronosis. Methods: We conducted a structured search in PubMed, Embase, PMC, Scielo, Elselvier, BMJ Case Reports, Journal of Medical Case Reports, Cases Journal and International Medical Case Reports Journal, from January 2000 to March 2016, exogenous ochronosis patients, between 18 to 70 years old, treated with laser QS. The articles were evaluated by the assessment tool validity and educational value of case reports described by Pierson (3). Results: 256 items found, after evaluation of the summary 63 articles were selected, 28 were duplicated, and 31 were excluded for not meeting inclusion criteria. 4 articles reporting 12 cases of patients with exogenous ochronosis diagnosed by histopathology and treated with laser QS were selected. Discussion: There is little experience with laser QS en OE. In clinical practice used for tattoos and dermal pigmentary diseases with satisfactory results. The dermal pigment OE and short laser pulse duration QS could be the mainstay of treatment for OE. Conclusion: The use of QS laser can be useful for the management of patients with OE, level of evidence 3 and grade of recommendation D. It is suggested to perform clinical studies with greater evidence.

Formato

application/pdf

Identificador

http://repository.urosario.edu.co/handle/10336/12309

Idioma(s)

spa

Publicador

Facultad de Medicina

Direitos

info:eu-repo/semantics/embargoedAccess

Fonte

instname:Universidad del Rosario

reponame:Repositorio Institucional EdocUR

1. Tan SK. Exogenous ochronosis in ethnic Chinese Asians: A clinicopathological study, diagnosis and treatment. J Eur Acad Dermatology Venereol. 2011;25(7):842–50.

2. Martins VMR, Diogenes de Sausa AR, Portela N de C, Tigre CAF, Goncalves LMS, Filho RJ de L. Exogenous ochronosis : case report and literature review. An Bras Dermatol. 2012;87(4):633–6.

3. Pierson DJ. How to read a case report (or teaching case of the month). RespirCare [Internet]. 2009;54(0020-1324 (Print)):1372–8. Available from: http://www.rcjournal.com/contents/10.09/10.09.1372.pdf

4. Tan S-K. Exogenous ochronosis--a diagnostic challenge. J Cosmet Dermatol. 2010;9(4):313–7.

5. Mishra SN, Dhurat RS, Deshpande DJ, Nayak CS. Diagnostic utility of dermatoscopy in hydroquinone-induced exogenous ochronosis. Int J Dermatol. 2013;52(4):413–7

6. Levin CY, Maibach H. Exogenous Ochronosis. An update on clinical features , causative agents and treatment options. Am J Clin Dermatol. 2001;2(4):213–7.

7. Findlay GH, Morrison JG, Simson IW. Exogenous ochronosis and pigmented colloid milium from hydroquinone bleaching creams. Br J Dermatol [Internet]. 1975;93(6):613–22. Available from: http://www.ncbi.nlm.nih.gov/pubmed/1220808

8. Bongiorno MR, Aricò M. Exogenous ochronosis and striae atrophicae following the use of bleaching creams. Int J Dermatol. 2005;44(2):112–5.

9. Levitt J. The safety of hydroquinone: A dermatologist’s response to the 2006 Federal Register. J Am Acad Dermatol. 2007;57(5):854–72.

10. Charlín R, Barcaui CB, Kac BK, Soares DB, Rabello-fonseca R, Azulay-abulafia L. Hydroquinone-induced exogenous ochronosis: A report of four cases and usefulness of dermoscopy. Int J Dermatol. 2008;47(1):19–23.

11. Tse TW. Hydroquinone for skin lightening: safety profile, duration of use and when should we stop? J Dermatolog Treat [Internet]. 2010;21(5):272–5. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20095963

12. Chaptini C, Huilgol SC. Erbium-doped yttrium aluminium garnet ablative laser treatment for endogenous ochronosis. Australas J Dermatol [Internet]. 2015;56(3):212–4. Available from: http://doi.wiley.com/10.1111/ajd.12199

13. Enfermedades HG De, Enfermedades HG De. Ocronosis exógena: informe de un caso. 2014;12(3):199–202.

14. AN K. The evolution of melasma therapy: targeting melanosomes using low-fluence Q-switched neodymium-doped yttrium aluminium garnet lasers. Semin Cutan Med Surg. 2012;2(31):126–32

15. Ayarza JRC, Restrepo C. Caso clínico Ocronosis: experiencia en el uso de luz pulsada intensa en dos pacientes. 2010;54(5):291–4

16. Gil I, Segura S, Martínez-Escala E, Lloreta J, Puig S, Vélez M, Pujol RM H-GJ. Dermoscopic and Reflectance Confocal Microscopic Features of Exogenous Ochronosis. Arch Dermatol. 2010;9(146):1021–5.

17. Ortonne JP, Arellano I, Berneburg M, Cestari T, Chan H, Grimes P, et al. A global survey of the role of ultraviolet radiation and hormonal influences in the development of melasma. J Eur Acad Dermatol Venereol. 2009;23(11):1254–62.

18. Ikino JK, Priscilla V, Fröde TS. Melasma and assessment of the quality of life in Brazilian women *. An Bras Dermatol. 2015;90(2):196–200.

19. Handel AC, Miot LDB, Miot HA. Melasma: A clinical and epidemiological review. An Bras Dermatol. 2014;89(5):771–82.

20. Tan S-K (SK). Exogenous ochronosis – successful outcome after treatment with Q-switched Nd:YAG laser. J Cosmet Laser Ther [Internet]. 2013;15(5):274–8. Available from: http://www.tandfonline.com/doi/full/10.3109/14764172.2012.758379

21. Anderson RR, Margolis RJ, Watenabe S, Flotte T, Hruza GJ, Dover JS. Selective photothermolysis of cutaneous pigmentation by Q-switched Nd: YAG laser pulses at 1064, 532, and 355 nm. J Invest Dermatol. Elsevier Masson SAS; 1989;93(1):28–32.

22. Choudhary S, Elsaie ML, Leiva A, Nouri K. Lasers for tattoo removal: A review. Lasers Med Sci. 2010;25(5):619–27.

23. Kramer K. Exogenous ochronosis. J AM ACAD DERMATOL. 2000;(42):869.71.

24. Bellew SG, Alster TS. Treatment of Exogenous Ochronosis with a Q-Switched Alexandrite (755 nm) Laser. Dermatologic Surg. 2004;30(4 I):555–8.

25. Polnikorn N. Treatment of refractory melasma with the MedLite C6 Q-switched Nd:YAG laser and alpha arbutin: a prospective study. J Cosmet Laser Ther [Internet]. 2010;12(3):126–31. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=20482238

26. Dhurat R, Mishra S, Nayak C, Deshpande D. Diagnostic utility of dermatoscopy in hydroquinone induced exogenous ochronosis. 21st Int Pigment Cell Conf Ski Other Pigment Cells Bridg Clin Med Sci. 2013;Bordeaux; :CS3 / C9 – .

27. Bhattar PA. Exogenous Ochronosis. Indian J Dermatol. 2015;60(6):537–43.

28. Romero SAR, Pereira RPM, Mariano AVDO, Francesconi F, Francesconi VA. Use of dermoscopy for diagnosis of exogenous ochronosis. An Bras Dermatol. 2011;86:31–4.

29. Gil I, Segura S, Martínez-Escala E, Lloreta J, Puig S, Vélez M, et al. Dermoscopic and reflectance confocal microscopic features of exogenous ochronosis. Arch Dermatol. 2010;146(9):1021–5.

30. Pai S, Shenoi S, Jain A. Exogenous ochronosis. Indian J Dermatology, Venereol Leprol [Internet]. 2013;79(4):522. Available from: http://www.ijdvl.com/text.asp?2013/79/4/522/113086

31. Kanechorn-Na-Ayuthaya P, Niumphradit N, Aunhachoke K, Nakakes A, Sittiwangkul R, Srisuttiyakorn C. Effect of combination of 1064 nm Q-switched Nd:YAG and fractional carbon dioxide lasers for treating exogenous ochronosis. J Cosmet Laser Ther [Internet]. 2013;15(1):42–5. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23368689

32. Grímes D. Descriptive studies: what they can and cannot do. Lancet. 2002;359(9301):145–9.

33. Daniela Prsico T, David Torres P. Niveles de evidencia y grados de recomendación: el sistema grade. Rev Chil Anest. 2014;43(4):357–60.

TEME

Palavras-Chave #Enfermedades de la Piel #Dermatología #616.5 #Exogenous ochronosis #Melasma #Hyperpigmentation #Q-switched laser #Hydroquinone
Tipo

info:eu-repo/semantics/bachelorThesis

info:eu-repo/semantics/acceptedVersion