An aggravated trajectory of depression and anxiety co-morbid with Hepatitis C: a within-groups study of 61 Australian outpatients.
Data(s) |
01/01/2015
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Resumo |
BACKGROUND: This study aimed to explore the course of depression and anxiety in chronic hepatitis C patients. METHODS: Data were combined from two studies: (1) Hospital Anxiety and Depression Scale (HADS) scores in 395 consecutive Australian outpatients from 2006 to 2010 formed the baseline measurement; and (2) Depression Anxiety Stress Scales (DASS) scores in a survey of a sub-sample of these patients in 2011 formed the follow-up measurement. After converting DASS to HADS scores, changes in symptom scores and rates of case-ness (≥8), and predictors of follow-up symptoms were assessed. RESULTS: Follow-up data were available for 61 patients (70.5% male) whose age ranged from 24.5 to 74.6 years (M=45.6). The time to follow-up ranged from 20.7 to 61.9 months (M=43.8). Baseline rates of depression (32.8%) and anxiety (44.3%) increased to 62.3% and 67.2%, respectively. These findings were confirmed, independent of the conversion, by comparing baseline HADS and follow-up DASS scores with British community norms. Baseline anxiety and younger age predicted depression, while baseline anxiety, high school non-completion, and single relationship status predicted anxiety. CONCLUSION: This study demonstrated a worsening trajectory of depression and anxiety. Further controlled and prospective research in a larger sample is required to confirm these findings. |
Identificador | |
Idioma(s) |
eng |
Publicador |
Bentham Open |
Relação |
http://dro.deakin.edu.au/eserv/DU:30088631/mikockas-walus-anaggravated-2015.pdf http://www.dx.doi.org/10.2174/1745017901511010174 |
Direitos |
2015, Bentham Open |
Palavras-Chave | #Anxiety #depression #hepatitis C #prognosis #trajectory. |
Tipo |
Journal Article |