Coexistence of mcr-1 and blaNDM-1 in Escherichia coli from Venezuela
| Data(s) |
01/10/2016
|
|---|---|
| Resumo |
We studied the presence of the mobile colistin resistance gene mcr-1 in human, animal, and environmental Enterobacteriaceae samples from Cumana, Venezuela, that were collected in 2015. The mcr-1 gene was detected in 2/93 Escherichia coli isolates from swine (novel ST452) and human (ST19) samples that were resistant to colistin. Whole-genome sequencing and transformation experiments identified mcr-1 on an IncI2 plasmid. One of the isolates also bore the widely spread carbapenemase NDM-1. A One Health approach is necessary to further elucidate the flux of these high-risk genes. |
| Formato |
application/pdf |
| Identificador | |
| Idioma(s) |
en |
| Publicador |
American Society for Microbiology |
| Relação |
http://eprints.ucm.es/39608/ http://aac.asm.org/content/60/10/6356.long 10.1128/AAC.01319-16 info:eu-repo/grantAgreement/EC/FP7/613754 282004 |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Palavras-Chave | #Veterinaria |
| Tipo |
info:eu-repo/semantics/article PeerReviewed |
