Monodisperse aqueous microspheres encapsulating high concentration of l-ascorbic acid: insights of preparation and stability evaluation from straight-through microchannel emulsification
Data(s) |
01/01/2015
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Resumo |
Stabilization of l-ascorbic acid (⌊-AA) is a challenging task for food and pharmaceutical industries. The study was conducted to prepare monodisperse aqueous microspheres containing enhanced concentrations of ⌊-AA by using microchannel emulsification (MCE). The asymmetric straight-through microchannel (MC) array used here constitutes 11 × 104 μm microslots connected to a 10 μm circular microholes. 5-30% (w/w) ⌊-AA was added to a Milli-Q water solution containing 2% (w/w) sodium alginate and 1% (w/w) magnesium sulfate, while the continuous phase constitutes 5% (w/w) tetraglycerol condensed ricinoleate in water-saturated decane. Monodisperse aqueous microspheres with average diameters (dav) of 18.7-20.7 μm and coefficients of variation (CVs) below 6% were successfully prepared via MCE regardless of the ⌊-AA concentrations applied. The collected microspheres were physically stable in terms of their dav and CV for >10 days of storage at 40°C. The aqueous microspheres exhibited ⌊-AA encapsulation efficiency exceeding 70% during the storage. |
Identificador | |
Idioma(s) |
eng |
Publicador |
Taylor & Francis |
Relação |
http://dro.deakin.edu.au/eserv/DU:30086036/khalid-monodisperseaqeuousmicrosph-2015.pdf http://www.dx.doi.org/10.1080/09168451.2015.1050988 |
Direitos |
2015, Japan Society for Bioscience, Biotechnology, and Agrochemistry |
Palavras-Chave | #monodisperse microspheres #L-ascorbic acid #high concentration #stability #sodium alginate |
Tipo |
Journal Article |