Anodal transcranial direct current stimulation of the motor cortex increases cortical voluntary activation and neural plasticity
Data(s) |
01/11/2016
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Resumo |
INTRODUCTION: We examined the cumulative effect of 4 consecutive bouts of non-invasive brain stimulation on corticospinal plasticity and motor performance, and whether these responses were influenced by the brain-derived neurotrophic factor (BDNF) polymorphism. <br /><br />METHODS: In a randomized double-blinded cross-over design, changes in strength and indices of corticospinal plasticity were analyzed in 14 adults who were exposed to 4 consecutive sessions of anodal and sham transcranial direct current stimulation (tDCS). Participants also undertook a blood sample for BDNF genotyping (N=13). <br /><br />RESULTS: We observed a significant increase in isometric wrist flexor strength with transcranial magnetic stimulation revealing increased corticospinal excitability, decreased silent period duration, and increased cortical voluntary activation compared to sham tDCS. <br /><br />DISCUSSION: The results show that 4 consecutive sessions of anodal tDCS increased cortical voluntary activation manifested as an improvement in strength. Induction of corticospinal plasticity appears to be influenced by the BDNF polymorphism. |
Identificador | |
Idioma(s) |
eng |
Publicador |
Wiley |
Relação |
http://dro.deakin.edu.au/eserv/DU:30082856/frazer-adonaltranscranial-2016.pdf http://dro.deakin.edu.au/eserv/DU:30082856/frazer-adonaltranscranial-preprint-2016.pdf http://dro.deakin.edu.au/eserv/DU:30082856/rantalainen-anodaltrans-inpress-2016.pdf http://www.dx.doi.org/10.1002/mus.25143 |
Direitos |
2016, Wiley |
Palavras-Chave | #BDNF polymorphism #cortical voluntary activation #motor performance #neural plasticity #strength #transcranial direct current stimulation |
Tipo |
Journal Article |