Discovering the effects of omega-3 and omega-6 fatty acids on allergy using a hek-blue cell line
Data(s) |
01/01/2014
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Resumo |
In recent times, allergy has become a financial, physical andpsychological burden to the society as a whole. Allergic reactions can result in life-threatening situations causing morbidity and high economic cost. Therefore, more effective reagents are needed for allergy treatment. Literature suggests that a causal relationship exists between the intake of Omega-3/6 fatty acids such as DHA, EPA, DPA and AA and atopic individuals suffering from allergies. In an allergic cascade, cytokines IL-4 and IL-13 bind to IL-4 receptor (IL-4R), which activates the STAT6 phosphorylation pathway leading to gene activation of allergen-specific IgE production by B cells. The overall aim of this study is to characterise Omega-3/6 fatty acids and their effects on IgE production. |
Identificador | |
Idioma(s) |
eng |
Publicador |
Wiley |
Relação |
http://dro.deakin.edu.au/eserv/DU:30072000/ahmed-dicoveringtheeffectsof-2014.pdf http://www.dx.doi.org/10.1111/imj.12548 |
Direitos |
2014, Royal Australasian College of Physicians |
Palavras-Chave | #Science & Technology #Life Sciences & Biomedicine #Medicine, General & Internal #General & Internal Medicine |
Tipo |
Conference Paper |