The mitogenome of Onchocerca volvulus from the Brazilian Amazonia focus


Autoria(s): Crainey, James L.; Silva, Túllio R.R. da; Encinas, Fernando; Marín, Michel A.; Vicente, Ana Carolina P.; Luz, Sérgio L.B.
Cobertura

Origin of publication: Brazil

Data(s)

10/07/2016

Resumo

We report here the first complete mitochondria genome of Onchocerca volvulus from a focus outside of Africa. An O. volvulus mitogenome from the Brazilian Amazonia focus was obtained using a combination of highthroughput and Sanger sequencing technologies. Comparisons made between this mitochondrial genome and publicly available mitochondrial sequences identified 46 variant nucleotide positions and suggested that our Brazilian mitogenome is more closely related to Cameroon-origin mitochondria than West African-origin mitochondria. As well as providing insights into the origins of Latin American onchocerciasis, the Brazilian Amazonia focus mitogenome may also have value as an epidemiological resource.

Formato

html

Identificador

http://www.bioline.org.br/abstract?id=oc16010

Idioma(s)

en

Publicador

Fundação Oswaldo Cruz, Fiocruz

Relação

http://memorias.ioc.fiocruz.br; http://www.bioline.org.br/oc

Direitos

Copyright 2016 - Memórias do Instituto Oswaldo Cruz

Fonte

Memórias do Instituto Oswaldo Cruz (ISSN: 1678-8060) Vol 111 Num 1

Palavras-Chave #Onchocerca volvulus mitochondria; onchocerciasis; Brazilian Amazonia focus; mitogenome
Tipo

RE