The effect of metoclopramide in capsule enteroscopy


Autoria(s): Almeida, N; Figueiredo, P; Freire, P; Lopes, S; Lérias, C; Gouveia, H; Leitão, MC
Data(s)

12/05/2016

12/05/2016

01/01/2010

Resumo

Clinical utility of prokinetics in capsule endoscopy (CE) is not clearly established. The objective of this prospective, randomized, single-blind, controlled trial was to determine if metoclopramide is useful in CE by increasing the rate of complete enteroscopy. Ninety-five patients referred for CE were randomized to no metoclopramide (group B, n = 48) or 10 mg metoclopramide (group A, n = 47). Complete enteroscopy was possible in 38 patients of group A (80.9%) and 37 of group B (77.1%) (P = 0.422) with two cases of gastric retention in group B (4.2%; P = 0.253). Median gastric transit time was 26 min (1-211) in group A and 28 min (4-200) in group B (P = 0.511). Mean small bowel transit time, calculated after excluding 20 patients with incomplete enteroscopy, was similar in both groups (221.2 +/- 89 min vs. 256 +/- 82.2 min; P = 0.083). There were also no differences in the total number of findings (group A 4.5 +/- 4.7; group B 4.7 +/- 3.7, P = 0.815). Administration of 10 mg metoclopramide orally 15 min before capsule ingestion did not significantly increase the rate of total enteroscopies and had no effect on transit times. It also did not modify CE diagnostic yield.

Identificador

Dig Dis Sci. 2010 Jan;55(1):153-7.

http://hdl.handle.net/10400.4/1918

10.1007/s10620-008-0687-y

Idioma(s)

eng

Direitos

openAccess

Palavras-Chave #Endoscopia por Cápsula #Metoclopramida #Pré-Medicação
Tipo

article