Biosynthesis of neocarazostatin A reveals the sequential carbazole prenylation and hydroxylation in the tailoring steps


Autoria(s): Huang, Sheng; Elsayed, Somayah Sameer; Lv, Meinan; Tabudravu, Jioji; Rateb, Mostafa E; Gyampoh, Roland; Kyeremeh, Kwaku; Ebel, Rainer; Jaspars, Marcel; Deng, Zixin; Yu, Yi; Deng, Hai
Contribuinte(s)

University of Aberdeen, Natural & Computing Sciences, Chemistry

Data(s)

05/08/2016

05/08/2016

17/12/2015

20/12/2017

Resumo

Acknowledgments Y.Y. acknowledges the financial support from “973” Program (2012CB721006) and National Natural Science Foundation of China (31570033). R.E., K.K., H.D., and M.J. acknowledge the financial support of the Leverhulme Trust-Royal Society Africa Award (AA090088).

Peer reviewed

Postprint

Formato

10

Identificador

Huang , S , Elsayed , S S , Lv , M , Tabudravu , J , Rateb , M E , Gyampoh , R , Kyeremeh , K , Ebel , R , Jaspars , M , Deng , Z , Yu , Y & Deng , H 2015 , ' Biosynthesis of neocarazostatin A reveals the sequential carbazole prenylation and hydroxylation in the tailoring steps ' Chemistry & Biology , vol 22 , no. 12 , pp. 1633-1642 . , 10.1016/j.chembiol.2015.10.012

1074-5521

PURE: 59328807

PURE UUID: f9cce7df-47da-4f82-84e6-84096e13ae81

http://hdl.handle.net/2164/6830

http://dx.doi.org/10.1016/j.chembiol.2015.10.012

Idioma(s)

eng

Relação

Chemistry & Biology

Direitos

© 2015. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/

Palavras-Chave #carbazole alkaloids #biosynthesis #prenyltransferase #reconstitution #P450 enzyme #neocarazostatin A #Q Science #Q
Tipo

Journal article