Are branched chain fatty acids the natural substrates for P450(BM3)?


Autoria(s): Cryle, Max J.; Espinoza, Rocio D.; Smith, Sarah J.; Matovic, Nicholas J.; De Voss, James J.
Data(s)

01/01/2006

Resumo

Branched chain fatty acids are substrates for cytochrome P450(BM3) (CYP102) from Bacillus megaterium; oxidation of C-15 and C-17 iso and anteiso fatty acids by P450(BM3) leads to the formation of hydroxylated products that possess high levels of regiochemical and stereochemical purity.

Identificador

http://espace.library.uq.edu.au/view/UQ:79578

Idioma(s)

eng

Publicador

Royal Society of Chemistry

Palavras-Chave #Chemistry, Multidisciplinary #Bacillus-megaterium #Cytochromes P450 #Subtilis #Purification #Cyclopropyl #Expression #Reduction #Oxidation #Alcohols #Ketones #C1 #250302 Biological and Medical Chemistry #780103 Chemical sciences
Tipo

Journal Article