When domestiques rebel: kinesins, cadherins and neuronal proliferation
Data(s) |
01/01/2005
|
---|---|
Resumo |
Conditional knockout of the KAP3 subunit from the kinesin motor KIF3 alters tissue patterning and causes abnormal proliferation of neural progenitor cells in the mouse brain. Impaired transport of N-cadherin to the surface of these cells may be one explanation for how such defects arise. |
Identificador | |
Idioma(s) |
eng |
Publicador |
Nature Publishing Group |
Palavras-Chave | #Cell Biology #Beta-catenin #Adhesion #Polarity #Activation #Induction #Complexes #Pathway #Disease #Growth #C1 #270105 Cellular Interactions (incl. Adhesion, Matrix, Cell Wall) #780105 Biological sciences |
Tipo |
Journal Article |