Microwave-assisted palladium-catalyzed highly regio- and stereoselective head to head dimerization of terminal aryl alkynes in water
| Contribuinte(s) |
Universidad de Alicante. Departamento de Química Orgánica Universidad de Alicante. Instituto Universitario de Síntesis Orgánica Síntesis Asimétrica (SINTAS) Catálisis Estereoselectiva en Síntesis Orgánica (CESO) |
|---|---|
| Data(s) |
03/12/2014
03/12/2014
15/09/2014
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| Resumo |
A highly regio- and stereoselective oxime palladacycle/imidazolinium-catalyzed head to head dimerization of terminal aryl alkynes in water is presented. The reaction, which is carried out at 130 °C under microwave irradiation in the presence of 1,3-bis-(2,6-diisopropylphenyl)imidazolinium chloride as ligand, triethylamine as base, and TBAB as surfactant, allows the synthesis of (E)-1,4-enynes as single stereoisomers in good isolated yields. Financial support from the MINECO (CTQ2010-20387), the Generalitat Valenciana (PROMETEO/2009/038), and the University of Alicante (VIGROB-173, UAUSTI13-01) is acknowledged. |
| Identificador |
RSC Advances. 2014, 4: 46508-46512. doi:10.1039/C4RA08287G 2046-2069 http://hdl.handle.net/10045/43022 10.1039/C4RA08287G |
| Idioma(s) |
eng |
| Publicador |
Royal Society of Chemistry |
| Relação |
http://dx.doi.org/10.1039/C4RA08287G |
| Direitos |
© Royal Society of Chemistry 2014 info:eu-repo/semantics/openAccess |
| Palavras-Chave | #Microwave-assisted #Palladium-catalyzed #Highly regio- and stereoselective #Head to head dimerization #Terminal aryl alkynes #Water #Química Orgánica |
| Tipo |
info:eu-repo/semantics/article |
