A review of clinical trial designs used to detect a disease-modifying effect of drug therapy in Alzheimer's disease and Parkinson's disease


Autoria(s): McGhee, David J. M.; Ritchie, Craig W.; Zajicek, John P.; Counsell, Carl E.
Data(s)

17/06/2016

17/06/2016

16/06/2016

Resumo

Acknowledgements This article presents independent research funded by the National Institute for Health Research (NIHR) under its Programme Grants for Applied Research Programme (Grant Reference Number RP-PG-0707-10124). The views expressed in this article are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health. The funders had no role in study design, data collection, data analysis, data interpretation, writing of the report or for the decision to submit for publication.

Peer reviewed

Publisher PDF

Identificador

McGhee , D J M , Ritchie , C W , Zajicek , J P & Counsell , C E 2016 , ' A review of clinical trial designs used to detect a disease-modifying effect of drug therapy in Alzheimer's disease and Parkinson's disease ' BMC Neurology , vol 16 , 92 . , 10.1186/s12883-016-0606-3

1471-2377

PURE: 67349397

PURE UUID: a254e3a3-e242-4d3b-b56a-14eb8056d2dd

http://hdl.handle.net/2164/6128

http://dx.doi.org/10.1186/s12883-016-0606-3

Idioma(s)

eng

Relação

BMC Neurology

Direitos

© 2016 The Author(s). Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Palavras-Chave #Alzheimer's disease #Parkinson's disease #disease progression #biomarkers #clinical trials #neuroprotective agents #R Medicine #R
Tipo

Journal article

Contribuinte(s)

University of Aberdeen, Medicine, Medical Sciences & Nutrition, Institute of Applied Health Sciences

University of Aberdeen, Medicine, Medical Sciences & Nutrition, Other Applied Health Sciences

University of Aberdeen, Chronic Disease Research Group

University of Aberdeen, Data Safe Haven