Viral Escape in the Central Nervous System with Multidrug-Resistant Human Immunodeficiency Virus-1
| Data(s) |
01/01/2016
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|---|---|
| Resumo |
In this study, we report the case of a patient infected with human immunodeficiency virus (HIV)-1 who developed ataxia and neurocognitive impairment due to viral escape within the central nervous system (CNS) with a multidrug-resistant HIV-1 despite long-term viral suppression in plasma. Antiretroviral therapy optimization with drugs with high CNS penetration led to viral suppression in the CSF, regression of ataxia, and improvement of neurocognitive symptoms. |
| Formato |
application/pdf |
| Identificador |
http://boris.unibe.ch/78641/1/ofv210.pdf Béguelin, Charles Antoine; Vázquez, Miriam; Bertschi, Manuel; Yerly, S; de Jong, Denise; Gutbrod, Klemens; Rauch, Andri; Cusini, Alexia (2016). Viral Escape in the Central Nervous System with Multidrug-Resistant Human Immunodeficiency Virus-1. Open Forum Infectious Diseases, 3(1), ofv210. Oxford University Press 10.1093/ofid/ofv210 <http://dx.doi.org/10.1093/ofid/ofv210> doi:10.7892/boris.78641 info:doi:10.1093/ofid/ofv210 info:pmid:26885540 urn:issn:2328-8957 |
| Idioma(s) |
eng |
| Publicador |
Oxford University Press |
| Relação |
http://boris.unibe.ch/78641/ |
| Direitos |
info:eu-repo/semantics/openAccess |
| Fonte |
Béguelin, Charles Antoine; Vázquez, Miriam; Bertschi, Manuel; Yerly, S; de Jong, Denise; Gutbrod, Klemens; Rauch, Andri; Cusini, Alexia (2016). Viral Escape in the Central Nervous System with Multidrug-Resistant Human Immunodeficiency Virus-1. Open Forum Infectious Diseases, 3(1), ofv210. Oxford University Press 10.1093/ofid/ofv210 <http://dx.doi.org/10.1093/ofid/ofv210> |
| Palavras-Chave | #610 Medicine & health |
| Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion PeerReviewed |
