FUNCTIONALIZATION OF CARBON NANOTUBES FOR MESENCHYMAL STEM CELL-ASSISTED PHOTOTHERMAL THERAPY
Data(s) |
01/01/2014
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Resumo |
Carbon nanotubes were first cut and functionalized with a newly developed reaction involving autoclaving and sonication in hydrogen peroxide. The functionalized nanotubes were characterized and evaluated for aqueous solubility. Studies which relate reaction conditions to final carbon nanotube length were conducted. Hydroxyl groups present on the carbon nanotubes served as a platform for a series of addition reactions, with the objective of conjugating streptavidin and fluorescent markers onto the carbon nanotubes. The modified nanotubes were attached onto the surface of biotinylated mesenchymal stem cells, creating a novel, tumor-homing delivery system for photothermal anticancer agents. |
Formato |
application/pdf |
Identificador |
http://digitalcommons.mtu.edu/etd-restricted/233 http://digitalcommons.mtu.edu/cgi/viewcontent.cgi?article=1233&context=etd-restricted |
Publicador |
Digital Commons @ Michigan Tech |
Fonte |
Dissertations, Master's Theses and Master's Reports - Restricted |
Palavras-Chave | #Carbon #Cell #Mesenchymal #Nanotube #Photothermal #Stem #Biomedical Engineering and Bioengineering #Chemical Engineering #Nanoscience and Nanotechnology |
Tipo |
text |