Robust Inferences For Covariate Effects On Survival Time With Censored Linear Regression Models


Autoria(s): Leon, Larry; Cai, Tianxi; Wei, L. J.
Data(s)

03/01/2005

Resumo

Various inference procedures for linear regression models with censored failure times have been studied extensively. Recent developments on efficient algorithms to implement these procedures enhance the practical usage of such models in survival analysis. In this article, we present robust inferences for certain covariate effects on the failure time in the presence of "nuisance" confounders under a semiparametric, partial linear regression setting. Specifically, the estimation procedures for the regression coefficients of interest are derived from a working linear model and are valid even when the function of the confounders in the model is not correctly specified. The new proposals are illustrated with two examples and their validity for cases with practical sample sizes is demonstrated via a simulation study.

Formato

application/pdf

Identificador

http://biostats.bepress.com/harvardbiostat/paper20

http://biostats.bepress.com/cgi/viewcontent.cgi?article=1020&context=harvardbiostat

Publicador

Collection of Biostatistics Research Archive

Fonte

Harvard University Biostatistics Working Paper Series

Palavras-Chave #Censored linear regression; Partial linear model; Resampling method; Rank estimation #Numerical Analysis and Computation #Statistical Methodology #Statistical Models #Statistical Theory #Survival Analysis
Tipo

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