Dynamic reorganization of flotillins in chemokine-stimulated human T-lymphocytes
| Data(s) |
2011
|
|---|---|
| Resumo |
Different types of membrane microdomains (rafts) have been postulated to be present in the rear and front of polarized migrating T-lymphocytes. Disruption of rafts by cholesterol sequestration prevents T-cell polarization and migration. Reggie/flotillin-1 and -2 are two highly homologous proteins that are thought to shape membrane microdomains. We have previously demonstrated the enrichment of flotillins in the uropod of human neutrophils. We have now investigated mechanisms involved in chemokine-induced flotillin reorganization in human T-lymphocytes, and possible roles of flotillins in lymphocyte polarization. |
| Formato |
application/pdf |
| Identificador |
http://boris.unibe.ch/5533/1/1471-2121-12-28.pdf Affentranger, Sarah; Martinelli, Sibylla; Hahn, Jonas; Rossy, Jérémie; Niggli, Verena (2011). Dynamic reorganization of flotillins in chemokine-stimulated human T-lymphocytes. BMC cell biology, 12, p. 28. London: BioMed Central 10.1186/1471-2121-12-28 <http://dx.doi.org/10.1186/1471-2121-12-28> doi:10.7892/boris.5533 info:doi:10.1186/1471-2121-12-28 info:pmid:21696602 urn:issn:1471-2121 |
| Idioma(s) |
eng |
| Publicador |
BioMed Central |
| Relação |
http://boris.unibe.ch/5533/ |
| Direitos |
info:eu-repo/semantics/openAccess |
| Fonte |
Affentranger, Sarah; Martinelli, Sibylla; Hahn, Jonas; Rossy, Jérémie; Niggli, Verena (2011). Dynamic reorganization of flotillins in chemokine-stimulated human T-lymphocytes. BMC cell biology, 12, p. 28. London: BioMed Central 10.1186/1471-2121-12-28 <http://dx.doi.org/10.1186/1471-2121-12-28> |
| Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion PeerReviewed |
