Psychiatric comorbidity, Restless Legs Syndrome and Nocturnal Eating Disorder: a case-control study
Contribuinte(s) |
Provini, Federica |
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Data(s) |
11/06/2013
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Resumo |
Objective: to evaluate the psychopathological profile in primary Restless Legs Syndrome (p-RLS) patients with and without nocturnal eating disorder (NED), analysing obsessive-compulsive traits, mood and anxiety disorder, and the two domains of personality proposed by Cloninger, temperament and character. Methods: we tested ten p-RLS patients without NED, ten p-RLS patients with NED and ten healthy control subjects, age and sex-matched, using Hamilton Depression and Anxiety Rating Scales, State-Trait Anxiety Inventory, Maudsley Obsessive Compulsive Inventory (MOCI) and Temperament and Character Inventory - revised (TCI). Results: p-RLS patients, particularly those with NED, had increased anxiety factor scores. MOCI-total, doubting and checking compulsion, and TCI-harm avoidance scores were significantly higher in p-RLS patients with NED. p-RLS patients without NED had significantly higher MOCI-doubting scores and a trend toward higher checking compulsion and harm avoidance scores with an apparent grading from controls to p-RLS patients without NED to p-RLS with NED. Conclusions: higher harm avoidance might predispose to display obsessive-compulsive symptoms, RLS and then, with increasing severity, compulsive nocturnal eating. RLS and NED could represent a pathological continuum in which a dysfunction in the limbic system, possibly driven by a dopaminergic dysfunction, could be the underlying pathophysiological mechanism. |
Formato |
application/pdf |
Identificador |
http://amsdottorato.unibo.it/5343/1/marconi_sara_tesi.pdf urn:nbn:it:unibo-10743 Marconi, Sara (2013) Psychiatric comorbidity, Restless Legs Syndrome and Nocturnal Eating Disorder: a case-control study , [Dissertation thesis], Alma Mater Studiorum Università di Bologna. Dottorato di ricerca in Scienze mediche specialistiche: progetto n. 2 "Medicina del sonno" <http://amsdottorato.unibo.it/view/dottorati/DOT438/>, 25 Ciclo. DOI 10.6092/unibo/amsdottorato/5343. |
Idioma(s) |
en |
Publicador |
Alma Mater Studiorum - Università di Bologna |
Relação |
http://amsdottorato.unibo.it/5343/ |
Direitos |
info:eu-repo/semantics/openAccess |
Palavras-Chave | #MED/26 Neurologia |
Tipo |
Tesi di dottorato NonPeerReviewed |