Epidemiological and molecular characterization of rubella virus isolated in Sao Paulo, Brazil during 1997-2004
Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
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Data(s) |
07/11/2013
07/11/2013
2012
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Resumo |
Rubella virus (RV) infection during the early stages of pregnancy can lead to serious birth defects, known as the congenital rubella syndrome (CRS). In 2003, the Pan American Health Organization (PAHO) adopted a resolution calling for the elimination of rubella and the congenital rubella syndrome (CRS) in the Americas by the year 2010. Brazil will have implemented the recommended PAHO strategy for elimination and interruption of endemic rubella virus transmission. The characterization of genotypes during the final stages of rubella elimination is important for determining whether new rubella isolates represent endemic transmission or importations. Samples (blood, urine, cerebrospinal fluid, and throat swabs) collected from patients with symptoms suggestive of rubella infection in 19972004 were isolated in cell culture and genotyped. Twenty-eight sequences were analyzed and two genotypes were identified: 1a and 1G. The information reported in this paper will contribute to understanding the molecular epidemiology of RV in Sao Paulo, Brazil. J. Med. Virol. 84:18311838, 2012. (c) 2012 Wiley Periodicals, Inc. |
Identificador |
JOURNAL OF MEDICAL VIROLOGY, HOBOKEN, v. 84, n. 11, supl. 1, Part 1, pp. 1831-1838, NOV, 2012 0146-6615 http://www.producao.usp.br/handle/BDPI/43006 10.1002/jmv.23393 |
Idioma(s) |
eng |
Publicador |
WILEY-BLACKWELL HOBOKEN |
Relação |
JOURNAL OF MEDICAL VIROLOGY |
Direitos |
closedAccess Copyright WILEY-BLACKWELL |
Palavras-Chave | #RUBELLA #VIRUS ISOLATION #GENOTYPES #RT-PCR #VIROLOGICAL SURVEILLANCE #VACCINATION #INFECTION #VIROLOGY |
Tipo |
article original article publishedVersion |