Serum C-reactive protein levels predict neurological outcome after aneurysmal subarachnoid hemorrhage
Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
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Data(s) |
05/11/2013
05/11/2013
2012
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Resumo |
Objectives: Our aim was to evaluate the relationship between serum C-reactive protein (CRP) levels and the neurological prognosis and development of vasospasm in patients with aneurysmal subarachnoid hemorrhage (aSAH). Methods: Eighty-two adult patients with aSAH diagnoses were prospectively evaluated. Glasgow Coma Scale (GCS) score, Hunt and Hess grade, Fisher grade, cranial CT scans, digital subtraction angiography studies and daily neurological examinations were recorded. Serial serum CRP measurements were obtained daily between admission and the tenth day. Glasgow Outcome Scale (GOS) and the modified Rankin Scale (mRS) were used to assess the prognosis. Results: Serum CRP levels were related to severity of aSAH. Patients with lower GCS scores and higher Hunt and Hess and Fisher grades presented statistically significant higher serum CRP levels. Patients with higher serum CRP levels had a less favorable prognosis. Conclusions: Increased serum CRP levels were strongly associated with worse clinical prognosis in this study. |
Identificador |
ARQUIVOS DE NEURO-PSIQUIATRIA, SAO PAULO SP, v. 70, n. 3, supl., Part 1-2, pp. 202-205, MAR, 2012 0004-282X http://www.producao.usp.br/handle/BDPI/41507 10.1590/S0004-282X2012000300009 |
Idioma(s) |
eng |
Publicador |
ASSOC ARQUIVOS NEURO- PSIQUIATRIA SAO PAULO SP |
Relação |
ARQUIVOS DE NEURO-PSIQUIATRIA |
Direitos |
openAccess Copyright ASSOC ARQUIVOS NEURO- PSIQUIATRIA |
Palavras-Chave | #C-REACTIVE PROTEIN #SUBARACHNOID HEMORRHAGE #VASOSPASM #INTRACRANIAL ANEURYSM #DELAYED CEREBRAL VASOSPASM #CORONARY-ARTERY-DISEASE #INTRACRANIAL ANEURYSMS #NITRIC-OXIDE #STROKE #PATHOPHYSIOLOGY #PREVENTION #NEUROSCIENCES #PSYCHIATRY |
Tipo |
article original article publishedVersion |