Ankle-Brachial Index: A Simple Way to Predict Mortality among Patients on Hemodialysis - A Prospective Study


Autoria(s): Cabrera Jimenez, Zaida Noemy; Pereira, Benedito Jorge; Romao, Joao Egidio, Jr.; da Silva Makida, Sonia Cristina; Abensur, Hugo; Affonso Moyses, Rosa Maria; Elias, Rosilene Motta
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

04/11/2013

04/11/2013

2012

Resumo

Background: Ankle-brachial index (ABI) can access peripheral artery disease and predict mortality in prevalent patients on hemodialysis. However, ABI has not yet been tested in incident patients, who present significant mortality. Typically, ABI is measured by Doppler, which is not always available, limiting its use in most patients. We therefore hypothesized that ABI, evaluated by a simplified method, can predict mortality in an incident hemodialysis population. Methodology/Principal Findings: We studied 119 patients with ESRD who had started hemodialysis three times weekly. ABI was calculated by using two oscillometric blood pressure devices simultaneously. Patients were followed until death or the end of the study. ABI was categorized in two groups normal (0.9-1.3) or abnormal (<0.9 and >1.3). There were 33 deaths during a median follow-up of 12 months (from 3 to 24 months). Age (1 year) (hazard of ratio, 1.026; p = 0.014) and ABI abnormal (hazard ratio, 3.664; p = 0.001) were independently related to mortality in a multiple regression analysis. Conclusions: An easy and inexpensive technique to measure ABI was tested and showed to be significant in predicting mortality. Both low and high ABI were associated to mortality in incident patients on hemodialysis. This technique allows nephrologists to identify high-risk patients and gives the opportunity of early intervention that could alter the natural progression of this population.

Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq), Brazil

Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPQ), Brazil

Identificador

PLOS ONE, SAN FRANCISCO, v. 7, n. 7, supl. 4, Part 1-2, pp. 69-78, 11140, 2012

1932-6203

http://www.producao.usp.br/handle/BDPI/37818

10.1371/journal.pone.0042290

http://dx.doi.org/10.1371/journal.pone.0042290

Idioma(s)

eng

Publicador

PUBLIC LIBRARY SCIENCE

SAN FRANCISCO

Relação

PLOS ONE

Direitos

openAccess

Copyright PUBLIC LIBRARY SCIENCE

Palavras-Chave #CHRONIC KIDNEY-DISEASE #BLOOD-PRESSURE INDEX #PULSE-WAVE VELOCITY #RENAL DATA SYSTEM #UNITED-STATES #CARDIOVASCULAR-DISEASE #DIALYSIS #HEALTH #MULTIDISCIPLINARY SCIENCES
Tipo

article

original article

publishedVersion