Susceptibility to toxoplasmic retinochoroiditis is associated with HLA alleles reported to be implicated with rapid progression to AIDS
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
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| Data(s) |
16/08/2013
16/08/2013
2012
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| Resumo |
Background/aims: The frequency of HLA markers associated with rapid progression to AIDS was evaluated in Brazilian patients with AIDS exhibiting or not toxoplasmic retinochoroiditis (TRC). Methods: 98 AIDS patients (25 with TRC, 43 with anti-T. gondii antibodies but without TCR, and 30 without anti-T. gondii antibodies and without TCR) were studied. Results: The HLA-B35 was significantly increased in TRC group (p = 0.0038). Conclusion: The presence of HLA-B35 may simultaneously predispose to progression to AIDS and TRC. FAPESP FAPESP CNPq CNPq |
| Identificador |
DISEASE MARKERS, AMSTERDAM, v. 33, n. 6, pp. 309-312, 2012 0278-0240 http://www.producao.usp.br/handle/BDPI/32605 10.3233/DMA-2012-00935 |
| Idioma(s) |
eng |
| Publicador |
IOS PRESS AMSTERDAM |
| Relação |
DISEASE MARKERS |
| Direitos |
closedAccess Copyright IOS PRESS |
| Palavras-Chave | #HLA #HIV #AIDS #TOXOPLASMIC RETINOCHOROIDITIS #TOXOPLASMA GONDII #HIV-1 INFECTION #OCULAR TOXOPLASMOSIS #DISEASE #GONDII #BIOTECHNOLOGY & APPLIED MICROBIOLOGY #GENETICS & HEREDITY #MEDICINE, RESEARCH & EXPERIMENTAL #PATHOLOGY |
| Tipo |
article original article publishedVersion |
