O emprego de hormônio luteinizante recombinante associado ao hormônio folículo-estimulante recombinante nos protocolos de estimulação ovariana com antagonista do GnRH


Autoria(s): Baruffi, Ricardo L.R.; Mauri, Ana L.; Petersen, Cláudia G.; Felipe, Valéria; Martins, Anice M.C.; Cornicelli, João; Cavagna, Mario; Oliveira, João B.A.; Franco Junior, Jose Gonçalves
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

27/05/2014

27/05/2014

01/10/2006

Resumo

The purpose of this investigation was to verify the efficacy of recombinant LH supplementation for controlled ovarian stimulation in GnRH-antagonist protocol for assisted reproductive technologies cycles. Search strategies included on-line surveys of databases from 1990 to 2006. In this review and meta-analysis, the observed advantages for the LH supplementation protocol were a higher serum estradiol levels on the day of hCG administration and a higher number of mature oocytes. However, there were no differences observed in the total amount of r-FSH administered, days of stimulation, number of oocyte retrieved, the clinical pregnancy rate per oocyte retrieval, the implantation rate and miscarriage rate. This result demonstrates that the association of r-LH with r-FSH may prevent any decrease in estradiol after antagonist administration and a significant higher number of mature oocytes was obtained. Nevertheless, additional randomized controlled trials are needed confirm these observations.

Formato

9-16

Identificador

https://www.academia.edu/3490307/ICSI-gestational_Carrier_Association_as_a_Strategy_for_Treatment_of_Mayer-_Rokitansky-Kuster-Hauser_Syndrome_Patients_Case_Report_and_Literature_Review

Jornal Brasileiro de Reproducao Assistida, v. 10, n. 4, p. 9-16, 2006.

1517-5693

1518-0557

http://hdl.handle.net/11449/69156

2-s2.0-33847306557

Idioma(s)

por

Relação

Jornal Brasileiro de Reproducao Assistida

Direitos

openAccess

Palavras-Chave #GnRH antagonist #Ovarian stimulation #Recombinant FSH #Recombinant LH #cetrorelix #chorionic gonadotropin #estradiol #ethinylestradiol #ethinylestradiol plus gestodene #gonadorelin antagonist #levonorgestrel #oral contraceptive agent #recombinant follitropin #recombinant luteinizing hormone #clinical trial #combination chemotherapy #data base #drug dose regimen #drug efficacy #drug mechanism #estradiol blood level #hormone substitution #human #low drug dose #meta analysis #monotherapy #oocyte #ovary function #pregnancy rate #spontaneous abortion #systematic review
Tipo

info:eu-repo/semantics/article