Optic neuropathy in sheep associated with overdosage of closantel
Contribuinte(s) |
Universidade Estadual Paulista (UNESP) |
---|---|
Data(s) |
27/05/2014
27/05/2014
01/12/1999
|
Resumo |
This report describes clinical and pathological findings in 2 flocks in Brazil where blindness and deaths in sheep occurred after closantel overdosage. Depression, weakness, and blindness affected 37 animals and 17 died in 2 flocks of 190 animals. Two animals submitted for ophthalmic examination showed no inflammation in the anterior segment of both eyes; posterior segment evaluation by indirect ophthalmoscopy suggested retinal degeneration. One postmortem evaluation local spongy vacuolization was in several regions of the brain and the optical nerves had severe axonal degeneration. |
Formato |
378-380 |
Identificador |
http://www.ion.org/publications/abstract.cfm?jp=p&articleID=9785 Veterinary and Human Toxicology, v. 41, n. 6, p. 378-380, 1999. 0145-6296 http://hdl.handle.net/11449/66027 WOS:000083906400008 2-s2.0-0345440136 |
Idioma(s) |
eng |
Relação |
Veterinary and Human Toxicology |
Direitos |
closedAccess |
Palavras-Chave | #closantel #animal experiment #blindness #clinical feature #depression #drug overdose #nerve degeneration #nonhuman #optic nerve disease #retina degeneration #sheep #Animals #Anthelmintics #Blindness #Brazil #Nerve Degeneration #Optic Nerve #Optic Nerve Diseases #Overdose #Retinal Degeneration #Salicylanilides #Sheep #Sheep Diseases |
Tipo |
info:eu-repo/semantics/article |