Isolation and evaluation of the antioxidant activity of phenolic constituents of the Garcinia brasiliensis epicarp
Contribuinte(s) |
Universidade Estadual Paulista (UNESP) |
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Data(s) |
20/05/2014
20/05/2014
01/06/2012
|
Resumo |
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) A new glycosylated biflavonone, morelloflavone-4 '''-O-beta-D-glycosyl, and the known compounds 1,3,6,7-tetrahydroxyxanthone, morelloflavone (fukugetin) and morelloflavone-7 ''-O-beta-D-glycosyl (fukugeside) were isolated from the epicarp of Garcinia brasiliensis collected in Brazil. The structures of these compounds were established using H-1 and C-13 NMR, COSY, gHMQC and gHMBC spectroscopy. The compounds exhibited antioxidant activity. The greatest potency was displayed by morelloflavone (2), with IC50 = 49.5 mM against DPPH and absorbance of 0.583 at 400 mu g/mL for the reduction of Fe3+. The weakest potency was displayed by 1,3,6,7-tetrahydroxyxanthone (1), with IC50 = 148 mM against DPPH and absorbance of 0.194 at 400 mu g/mL for the reduction of Fe3+. (C) 2011 Elsevier Ltd. All rights reserved. |
Formato |
1230-1235 |
Identificador |
http://dx.doi.org/10.1016/j.foodchem.2011.10.110 Food Chemistry. Oxford: Elsevier B.V., v. 132, n. 3, p. 1230-1235, 2012. 0308-8146 http://hdl.handle.net/11449/42633 10.1016/j.foodchem.2011.10.110 WOS:000301022400016 WOS000301022400016.pdf |
Idioma(s) |
eng |
Publicador |
Elsevier B.V. |
Relação |
Food Chemistry |
Direitos |
openAccess |
Palavras-Chave | #Garcinia brasiliensis #Biflavonoids #Natural products #Antioxidants |
Tipo |
info:eu-repo/semantics/article |