Isolation and evaluation of the antioxidant activity of phenolic constituents of the Garcinia brasiliensis epicarp


Autoria(s): Gontijo, Vanessa Silva; de Souza, Thiago Correa; Rosa, Isael Aparecido; Soares, Marisi Gomes; da Silva, Marcelo Aparecido; Vilegas, Wagner; Viegas Junior, Claudio; dos Santos, Marcelo Henrique
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

20/05/2014

20/05/2014

01/06/2012

Resumo

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A new glycosylated biflavonone, morelloflavone-4 '''-O-beta-D-glycosyl, and the known compounds 1,3,6,7-tetrahydroxyxanthone, morelloflavone (fukugetin) and morelloflavone-7 ''-O-beta-D-glycosyl (fukugeside) were isolated from the epicarp of Garcinia brasiliensis collected in Brazil. The structures of these compounds were established using H-1 and C-13 NMR, COSY, gHMQC and gHMBC spectroscopy. The compounds exhibited antioxidant activity. The greatest potency was displayed by morelloflavone (2), with IC50 = 49.5 mM against DPPH and absorbance of 0.583 at 400 mu g/mL for the reduction of Fe3+. The weakest potency was displayed by 1,3,6,7-tetrahydroxyxanthone (1), with IC50 = 148 mM against DPPH and absorbance of 0.194 at 400 mu g/mL for the reduction of Fe3+. (C) 2011 Elsevier Ltd. All rights reserved.

Formato

1230-1235

Identificador

http://dx.doi.org/10.1016/j.foodchem.2011.10.110

Food Chemistry. Oxford: Elsevier B.V., v. 132, n. 3, p. 1230-1235, 2012.

0308-8146

http://hdl.handle.net/11449/42633

10.1016/j.foodchem.2011.10.110

WOS:000301022400016

WOS000301022400016.pdf

Idioma(s)

eng

Publicador

Elsevier B.V.

Relação

Food Chemistry

Direitos

openAccess

Palavras-Chave #Garcinia brasiliensis #Biflavonoids #Natural products #Antioxidants
Tipo

info:eu-repo/semantics/article