Cadinane sesquiterpenoids of Phomopsis cassiae, an endophytic fungus associated with Cassia spectabilis (Leguminosae)


Autoria(s): Silva, Geraldo Humberto; Teles, Helder Lopes; Zanardi, Lisineia Maria; Marx Young, Maria Claudia; Eberlin, Marcos Nogueira; Hadad, Renato; Pfenning, Ludwig H.; Costa-Neto, Claudio Miguel; Castro-Gamboa, Ian; Bolzani, Vanderlan da Silva; Araujo, Angela Regina
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

20/05/2014

20/05/2014

01/09/2006

Resumo

Five cadinane sesquiterpenes derivatives were isolated by bioassay-guided fractionation from Phomopis cassiae, an endophytic fungus isolated from Cassia spectabilis. The structures of the two diastereoisomeric 3,9,12-trihydroxycalamenenes (1, 2); 3,12-dihydroxycalamenene (3); 3,12-dihydroxycadalene (4) and 3,11,12-trihydroxycadalene (5) were established on the basis of analyses of ID and 2D NMR and HRTOFMS experiments. Antifungal activity of the isolates was evaluated against Cladosporium sphaerospermum and Cladosporium cladosporioides, revealing 5 as the most active compound. (c) 2006 Elsevier Ltd. All rights reserved.

Formato

1964-1969

Identificador

http://dx.doi.org/10.1016/j.phytochem.2006.06.004

Phytochemistry. Oxford: Pergamon-Elsevier B.V., v. 67, n. 17, p. 1964-1969, 2006.

0031-9422

http://hdl.handle.net/11449/32274

10.1016/j.phytochem.2006.06.004

WOS:000240821700013

Idioma(s)

eng

Publicador

Elsevier B.V.

Relação

Phytochemistry

Direitos

closedAccess

Palavras-Chave #Phomopsis #endophytic fungi #Cadinane Sesquiterpenes #antifungal
Tipo

info:eu-repo/semantics/article