ANTIMICROBIAL ACTIVITY of CARPOLOBIA LUTEA EXTRACTS and FRACTIONS


Autoria(s): Nwidu, Lucky L.; Nwafor, Paul A.; Vilegas, Wagner
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

20/05/2014

20/05/2014

01/01/2012

Resumo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Carpolobia lutea (G. Don) (Polygalaceae) is a tropical medicinal plant putative in traditional medicines against gonorrhea, gingivitis, infertility, antiulcer and malaria. The present study evaluated the antimicrobial, antifungal and antihelicobacter effects of extracts C. lutea leaf, stem and root. The extracts were examined using the disc-diffusion and Microplates of 96 wells containing Muller-Hinton methods against some bacterial strains: Eschericia coli (ATCC 25922), E. coli (ATCC10418), Pseudomonas aeruginosa (ATCC 27853), Staphylococcus aureus (ATCC 25923), Staphyllococus aureus (ATCC 6571), Enterococcus faecalis (ATCC 29212) and Bacillus subtilis (NCTC 8853) and four clinical isolates: one fungi (Candida albican) and three bacteria (Salmonella, Sheigella and staphylococcus aureus). The Gram-positive bacteria: Staphylococcus aureus (ATCC 25923), Enterococcus faecalis (ATCC 29212), Bacillus subtilis (ATCC 19659) and the Gram-negative bacteria: Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Candida albicans (ATCC 18804) and Helicobacter pylori (ATCC 43504). Some of these extracts were found to be active against some tested strains but activity against H. pylori was > 1000mg/ml and good fungistatic activity against C. albican. The MIC against C. albican is in the order n-HF > CHF > ETF- EAF. The order of potency of fraction was the ethanol root > n-HF leaf > ethanol fraction stem > chloroform fraction leaf = ethyl acetate fraction leaf. Polyphenols were demonstrated in ethanol fraction, ethyl acetate fraction, crude ethyl acetate extract and ethanol extract, respectively. These polyphenols isolated may partly explain and support the use of C. lutea for the treatment of infectious diseases in traditional Ibibio medicine of Nigeria.

Formato

323-328

Identificador

http://dx.doi.org/10.4314/ajtcam.v9i3.4

African Journal of Traditional Complementary and Alternative Medicines. Ile-ife: African Networks Ethnomedicines, v. 9, n. 3, p. 323-328, 2012.

0189-6016

http://hdl.handle.net/11449/26357

10.4314/ajtcam.v9i3.4

WOS:000306123400004

Idioma(s)

eng

Publicador

African Networks Ethnomedicines

Relação

African Journal of Traditional Complementary and Alternative Medicines

Direitos

closedAccess

Palavras-Chave #Carpolobia lutea #Polygalaceae #antimicrobial #antifungal #antihelicobacter #Polyphenols
Tipo

info:eu-repo/semantics/article