Effects of Formulations Containing Dimethylaminoethanol (DMAE) Acetoamidobenzoate and Pidolate on the Skin


Autoria(s): Guimaraes, Gustavo N.; Chorilli, Marlus; Leonardi, Gislaine R.; Prestes, Paula S.; Garcia, Gislene; Pires-De-Campos, Maria S. M.; Polacow, Maria L. O.
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

20/05/2014

20/05/2014

01/05/2011

Resumo

The aim of this study was to analyze the effects of formulations containing DMAE pidolate and DMAE acetoamidobenzoate on the skin. Four areas of five swines were submitted to following treatments during 15 days: C (Control), S (Silicone = 80 % DC*LC Blend (R)), F1 (DMAE acetoamidobenzoate), F2 (DMAE pidolate). Measures of the thickness of epidermis and stratum corneum, and the density population of fibroblasts and leukocytes in papillary dermis were obtained. We also assessed possible variations in birefringence of dermis collagen bundles. Means of the data was compared using ANOVA followed by the Tukey test. The F1 and F2 groups showed a thicker epidermis than the control group (p < 0.01), but did not demonstrate a significant difference in the number of fibroblasts and leukocytes, as well as in the birefringent areas of collagen bundles, in comparison with the control groups. The DMAE-supplemented formulations enhanced viable epidermis thickness, but did not modify structures related with mechanical properties of the skin.

Formato

641-646

Identificador

http://sedici.unlp.edu.ar/bitstream/handle/10915/8195/Resumen.pdf?sequence=1

Latin American Journal of Pharmacy. La Plata: Colegio Farmaceuticos Provincia de Buenos Aires, v. 30, n. 4, p. 641-646, 2011.

0326-2383

http://hdl.handle.net/11449/7815

WOS:000294752700003

Idioma(s)

eng

Publicador

Colegio Farmaceuticos Provincia de Buenos Aires

Relação

Latin American Journal of Pharmacy

Direitos

closedAccess

Palavras-Chave #Dimethylaminoethanol #Histopatology #Skin
Tipo

info:eu-repo/semantics/article