PTEX characterisation and its role in Plasmodium virulence and survival


Autoria(s): Matthews, Kathryn
Contribuinte(s)

De Koning-Ward, Tania

Ming Kalanon

Data(s)

01/03/2015

Resumo

 Malaria parasites remodel erythrocytes for their survival. They passage proteins into the host cell via an export machinery known as PTEX. For the first time, this study shows that different types of parasite-exported proteins use PTEX. Importantly, new drugs can be developed which target PTEX components to eliminate an infection.

Identificador

http://hdl.handle.net/10536/DRO/DU:30079075

Idioma(s)

eng

Publicador

Deakin Univeristy, Faculty of Health, School of Medicine

Relação

http://dro.deakin.edu.au/eserv/DU:30079075/matthews-agreement-2015.pdf

http://dro.deakin.edu.au/eserv/DU:30079075/matthews-ptexcharacterisation-2015A.pdf

Direitos

The Author. All Rights Reserved

Palavras-Chave #malaria #plasmodium parasites #erythrocytes #putative export machinery (PTEX) #parasite-exported proteins #drug targeting
Tipo

Thesis