Expression of anti-viral shRNA molecules in transgenic zebrafish
| Contribuinte(s) |
Ward Alister C. |
|---|---|
| Data(s) |
01/04/2015
|
| Resumo |
Development of transgenic zebrafish specifically resistant to Viral Hemorrhagic Septicemia Virus mediated by short-hairpin RNA interference. Introduction of shRNAs by Tol2 transgenisis in to zebrafish overwhelmed multiple facets of the endogenous microRNA pathway including Exportin-5 and Argonaute-2 and prevented normal zebrafish development. |
| Identificador | |
| Idioma(s) |
eng |
| Publicador |
Deakin Univeristy, Faculty of Health, School of Medicine |
| Relação |
http://dro.deakin.edu.au/eserv/DU:30079001/clarke-agreement-2015.pdf http://dro.deakin.edu.au/eserv/DU:30079001/clarke-expressionof-2015A.pdf |
| Direitos |
The Author. All Rights Reserved |
| Palavras-Chave | #transgenic zebrafish #viral hemorrhagic septicemia virus #short-hairpin RNA interference |
| Tipo |
Thesis |
