Orally administered anti-cancer nanocarriers loaded with therapeutic proteins


Autoria(s): Mahidhara, V.N.L.Ganesh
Contribuinte(s)

Kanwar, Jagat

Kanwar (nee Kaur), Rupinder

Data(s)

01/05/2012

Resumo

 Anti-cancerous ability of orally fed therapeutic proteins was potentiated by further strengthening their digestive resistance by means of nano encapsulation. In this regard, formulation of a novel polymer encapsulated ceramic anti-cancer nanocarriers (ACSC NCs) loaded with anti-cancer proteins (Fe-bLf and SurR9-C84A) were synthesized. These NCs were successfully evaluated for their anti-cancer efficacy in vitro and in nude mice bearing human cancers.

Identificador

http://hdl.handle.net/10536/DRO/DU:30073444

Idioma(s)

eng

Publicador

Deakin University, Institute for Frontier Materials

Relação

http://dro.deakin.edu.au/eserv/DU:30073444/mahidhara-agreement-2012.pdf

http://dro.deakin.edu.au/eserv/DU:30073444/mahidhara-orallyadministered-2012A.pdf

Direitos

The Author. All Rights Reserved

Tipo

Thesis

Palavras-Chave #alginate enclosed chitosan coated ceramic nanocarriers #cancer therapy #drug delivery systems #nanotechnology