Orally administered anti-cancer nanocarriers loaded with therapeutic proteins
Contribuinte(s) |
Kanwar, Jagat Kanwar (nee Kaur), Rupinder |
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Data(s) |
01/05/2012
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Resumo |
Anti-cancerous ability of orally fed therapeutic proteins was potentiated by further strengthening their digestive resistance by means of nano encapsulation. In this regard, formulation of a novel polymer encapsulated ceramic anti-cancer nanocarriers (ACSC NCs) loaded with anti-cancer proteins (Fe-bLf and SurR9-C84A) were synthesized. These NCs were successfully evaluated for their anti-cancer efficacy in vitro and in nude mice bearing human cancers. |
Identificador | |
Idioma(s) |
eng |
Publicador |
Deakin University, Institute for Frontier Materials |
Relação |
http://dro.deakin.edu.au/eserv/DU:30073444/mahidhara-agreement-2012.pdf http://dro.deakin.edu.au/eserv/DU:30073444/mahidhara-orallyadministered-2012A.pdf |
Direitos |
The Author. All Rights Reserved |
Tipo |
Thesis |
Palavras-Chave | #alginate enclosed chitosan coated ceramic nanocarriers #cancer therapy #drug delivery systems #nanotechnology |