Fe-bLf nanoformulation targets survivin to kill colon cancer stem cells and maintains absorption of iron, calcium and zinc
| Data(s) |
01/01/2015
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|---|---|
| Resumo |
To validate the anticancer efficacy of alginate-enclosed, chitosan-conjugated, calcium phosphate, iron-saturated bovine lactoferrin (Fe-bLf) nanocarriers/nanocapsules (NCs) with improved sustained release and ability to induce apoptosis by downregulating survivin, as well as cancer stem cells. |
| Identificador | |
| Idioma(s) |
eng |
| Publicador |
Future Medicine |
| Relação |
http://dro.deakin.edu.au/eserv/DU:30071104/kanwar-feblfnanoformulation-2014.pdf http://www.dx.doi.org/10.2217/nnm.14.132 http://www.ncbi.nlm.nih.gov/pubmed/25017148 |
| Direitos |
2014, Future Medicine |
| Palavras-Chave | #Fe-bLf #absorption #iron metabolism #miRNA #nanocarriers/nanocapsules #nanotoxicity #oral delivery #stem cell #survivin #xenograft #Science & Technology #Life Sciences & Biomedicine #Biotechnology & Applied Microbiology #Nanoscience & Nanotechnology #Science & Technology - Other Topics #nanocarriers #nanocapsules #ANTIOXIDANT ENZYME-ACTIVITIES #GUT EPITHELIAL-CELLS #TRANSFERRIN RECEPTOR #OXIDATIVE STRESS #DRUG-DELIVERY #TRANSPORTER 1 #CACO-2 CELLS #NUDE-MICE #IN-VITRO |
| Tipo |
Journal Article |
