Peanut allergens alter intestinal barrier permeability and tight junction localisation in Caco-2 cell cultures
Data(s) |
01/01/2014
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Resumo |
Allergen absorption by epithelia may play an important role in downstream immune responses. Transport mechanisms that can bypass Peyer's patches include transcellular and paracellular transport. The capacity of an allergen to cross via these means can modulate downstream processing of the allergen by the immune system. The aim of this study was to investigate allergen-epithelial interactions of peanut allergens with the human intestinal epithelium. |
Identificador | |
Idioma(s) |
eng |
Publicador |
S. Karger AG |
Relação |
http://dro.deakin.edu.au/eserv/DU:30070301/ackland-peanutallergens-2014.pdf http://www.dx.doi.org/10.1159/000362956 http://www.ncbi.nlm.nih.gov/pubmed/24923432 |
Direitos |
2014, S. Karger AG |
Palavras-Chave | #Allergen #Caco-2 #Epithelia #Peanut #Permeability #Tight junction #Transport #Science & Technology #Life Sciences & Biomedicine #Cell Biology #Physiology #ARA H 1 #IGE-BINDING EPITOPES #COLORECTAL-CANCER CELLS #MAJOR SOYBEAN ALLERGEN #ADHESION MOLECULE #EPITHELIAL-CELLS #IN-VITRO #MUTATIONAL ANALYSIS #ENDOTHELIAL-CELLS #CHOLERA-TOXIN |
Tipo |
Journal Article |