STin2 VNTR polymorphism is associated with comorbid tobacco use and mood disorders.


Autoria(s): Pizzo de Castro,MR; Vargas Nunes,SO; Guembarovski,RL; Ariza,CB; Oda,JM; Vargas,HO; Piccoli de Melo,LG; Watanabe,MA; Berk,M; Maes,M
Data(s)

01/02/2015

Resumo

There is a significant comorbidity between mood disorders and tobacco use disorder (TUD), which may be related to both genetic and environmental factors. Gene variants of the 5-HT transporter, such as STin2 VNTR (a variable number of tandem repeats in the functional serotonin transporter intron 2) may be associated with mood disorders and TUD.

Identificador

http://hdl.handle.net/10536/DRO/DU:30069442

Idioma(s)

eng

Publicador

Elsevier

Relação

http://dro.deakin.edu.au/eserv/DU:30069442/pizodecastro-stinvntr-2014.pdf

http://www.dx.doi.org/10.1016/j.jad.2014.10.023

http://www.ncbi.nlm.nih.gov/pubmed/25451436

Direitos

2015, Elsevier

Palavras-Chave #Genetic polymorphism #Inflammation #Mood disorders #Oxidative stress #Serotonin transporter #Tobacco use disorder #Science & Technology #Life Sciences & Biomedicine #Clinical Neurology #Psychiatry #Neurosciences & Neurology #SEROTONIN TRANSPORTER GENE #MAJOR DEPRESSIVE DISORDER #OBSTRUCTIVE PULMONARY-DISEASE #CIGARETTE-SMOKING #NICOTINE-DEPENDENCE #BIPOLAR DISORDER #FOLLOW-UP #PSYCHIATRIC-DISORDERS #SUICIDAL-BEHAVIOR #MENTAL-HEALTH
Tipo

Journal Article