Mid-femoral and mid-tibial muscle cross-sectional area as predictors of tibial bone strength in middle-aged and older men
Data(s) |
01/01/2013
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Resumo |
While it is widely acknowledged that bones adapt to the site-specific prevalent loading environment, reasonable ways to estimate skeletal loads are not necessarily available. For long bone shafts, muscles acting to bend the bone may provide a more appropriate surrogate of the loading than muscles expected to cause compressive loads. Thus, the aim of this study was to investigate whether mid-thigh muscle cross-sectional area (CSA) was a better predictor of tibial mid-shaft bone strength than mid-tibia muscle CSA in middle aged and older men. 181 Caucasian men aged 50–79 years (mean±SD; 61±7 years) participated in this study. Mid-femoral and mid-tibial bone traits cortical area , density weighted polar moment of area and muscle CSA [cm²] were assessed with computed tomography. Tibial bone traits were positively associated with both the mid-femur (r=0.44 to 0.46, P<0.001) and the mid-tibia muscle CSA (r=0.35 to 0.37, P<0.001). Multivariate regression analysis, adjusting for age, weight, physical activity and femoral length, indicated that mid-femur muscle CSA predicted tibial mid-shaft bone strength indices better thn mid-tibia muscle CSA. In conclusion, the association between a given skeletal site and functionally adjacent muscles may provide a meaningful probe of the site-specific effect of loading on bone. |
Identificador | |
Idioma(s) |
eng |
Publicador |
International Society of Musculoskeletal and Neuronal Interactions |
Relação |
http://dro.deakin.edu.au/eserv/DU:30060427/rantalainen-midfemoraland-2013.pdf http://www.ismni.org/jmni/ |
Direitos |
2013, International Society of Musculoskeletal and Neuronal Interactions |
Palavras-Chave | #Muscle Cross-Sectional #Bone Strength #QCT #Older Men #Muscle-Bone Interaction |
Tipo |
Journal Article |