The Ikaros gene family
| Data(s) |
01/01/2010
|
|---|---|
| Resumo |
Ikaros-related transcription factors are essential for adaptive immunity. Evolutionary analysis suggested derivation from a precursor similar to the 'atypical' Pegasus protein, and possibly related to invertebrate Hunchback. Pegasus was shown to regulate neural, gut and blood cell development in zebrafish, with Ikaros identified as one of several potential gene targets. |
| Identificador | |
| Idioma(s) |
eng |
| Publicador |
Deakin University, Faculty of Health, Medicine, Nursing and Behavioural Sciences, School of Medicine |
| Palavras-Chave | #Transcription factors #Immune response - Regulation - Genetic aspects #Hematopoiesis - Genetic aspects |
| Tipo |
Thesis |
