Analysis of the Stat5 genes in zebrafish
| Data(s) |
01/01/2006
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|---|---|
| Resumo |
This dissertation identified and characterised a key genetic regulator called Stat5 using zebrafish. Up-regulation of Stat5 led to an increase in blood cells, indicative of pre-leukaemia, whilst down-regulation decreased these cells and caused other defects. This work shows that Stat5 is critical in blood cell maturation and early embryonic development. |
| Identificador | |
| Idioma(s) |
eng |
| Publicador |
Deakin University, Faculty of Science and Technology, School of Life and Environmental Sciences |
| Palavras-Chave | #Genetic regulation #Gene expression #Hematopoietic system |
| Tipo |
Thesis |
