Optimal H∞ insulin injection control for blood glucose regulation in diabetic patients
Data(s) |
01/10/2005
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Resumo |
The theory of H/sup /spl infin// optimal control has the feature of minimizing the worst-case gain of an unknown disturbance input. When appropriately modified, the theory can be used to design a "switching" controller that can be applied to insulin injection for blood glucose (BG) regulation. The "switching" controller is defined by a collection of basic insulin rates and a rule that switches the insulin rates from one value to another. The rule employed an estimation of BG from noisy measurements, and the subsequent optimization of a performance index that involves the solution of a "jump" Riccati differential equation and a discrete-time dynamic programming equation. With an appropriate patient model, simulation studies have shown that the controller could correct BG deviation using clinically acceptable insulin delivery rates. <br /> |
Identificador | |
Idioma(s) |
eng |
Publicador |
IEEE Xplore |
Relação |
http://dro.deakin.edu.au/eserv/DU:30008902/nahavandi-optimalH-2005.pdf http://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=01510846 |
Direitos |
2005, IEEE |
Tipo |
Journal Article |