An epoxide ring-opening approach for a short and stereoselective synthesis of icetexane diterpenoids


Autoria(s): CARITA, Adriana; BURTOLOSO, Antonio C. B.
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

20/10/2012

20/10/2012

2010

Resumo

A new approach for the synthesis of the core skeleton of icetexane diterpenoids is presented and deals with an epoxide ring-opening reaction by metallated aromatic compounds. Employing this strategy, a short synthesis of an icetexane analogue of brussonol was achieved in just four steps from 2-allyl-cyclohexanone. (C) 2009 Elsevier Ltd. All rights reserved.

FAPESP

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

CNPq

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Identificador

TETRAHEDRON LETTERS, v.51, n.4, p.686-688, 2010

0040-4039

http://producao.usp.br/handle/BDPI/31687

10.1016/j.tetlet.2009.11.108

http://dx.doi.org/10.1016/j.tetlet.2009.11.108

Idioma(s)

eng

Publicador

PERGAMON-ELSEVIER SCIENCE LTD

Relação

Tetrahedron Letters

Direitos

closedAccess

Copyright PERGAMON-ELSEVIER SCIENCE LTD

Palavras-Chave #(+/-)-ABROTANONE #(+/-)-BRUSSONOL #KOMAROVIQUINONE #Chemistry, Organic
Tipo

article

original article

publishedVersion