Prevalence of hepatitis B and C serological markers among first-time blood donors in Brazil: A multi-center serosurvey
Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
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Data(s) |
20/10/2012
20/10/2012
2008
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Resumo |
Little data are available on the seroprevalence of, and risk factors for hepatitis B and C viruses (HBV and HCV) infection in Latin American countries. A multi-center serosurvey was conducted among 3,598 first-time blood donors (65% men) from Sao Paulo, Salvador and Manaus in Brazil. The gender-specific seroprevalences of antibodies against hepatitis B core antigen (anti-HBc) and of the hepatitis B surface antigen (HBsAg) in anti-HBc-positive sera were measured, and risk factors analyzed by gender. The gender-specific seroprevalences of antibodies against HCV (anti-HCV) were measured, but risk factors for HCV were not determined. Anti-HBc and HBsAg seroprevalences were not significantly different in men [101/2,341 (4.31%) and 4/2,229 (0.18%), respectively] and women [65/1,237 (5.25%) and 8/ 1,169 (0.68%), respectively], whereas the seroprevalence of anti-HCV was higher in women (12/1,238 [0.97%] vs. 9/2,353 [0.38%]; odds ratio [OR] = 2.49; 95% confidence interval [Cl]: 1.0-6.0). No significant difference for HBV infection was found across the three study sites or by ethnic group. The seroprevalence of anti-HBc increased with age, but decreased with education level in both genders. Lifetime number of sexual partners was associated with anti-HBc prevalence among men (OR = 1.95; 95% Cl: 1.2-3.1), but not women. The seroprevalence of HBV and HCV was low among Brazilian blood donors, and exposure increased with age in both genders. |
Identificador |
JOURNAL OF MEDICAL VIROLOGY, v.80, n.1, p.53-57, 2008 0146-6615 http://producao.usp.br/handle/BDPI/30800 10.1002/jmv.21046 |
Idioma(s) |
eng |
Publicador |
WILEY-LISS |
Relação |
Journal of Medical Virology |
Direitos |
restrictedAccess Copyright WILEY-LISS |
Palavras-Chave | #hepatitis B virus (HBV) #hepatitis C virus (HCV) #epidemiology #seroprevalence #blood donors #Brazil #VIRUS-INFECTION #UNITED-STATES #RISK #Virology |
Tipo |
article original article publishedVersion |