Brazilian red propolis: unreported substances, antioxidant and antimicrobial activities
Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
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Data(s) |
20/10/2012
20/10/2012
2011
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Resumo |
BACKGROUND: Chloroform, ethyl acetate and methanol extracts of a sample of red propolis from the state of Alagoas (northeast Brazil) were analyzed by gas chromatography-mass spectrometry and high-performance liquid chromatography-diode array detection-electrospray ionization-mass spectrometry. Antimicrobial and antioxidant activities were also obtained. RESULTS: The propolis sample contained low content of narigenin-8-C-hexoside, this being the first report of a C-glycoside in propolis. The main constituent found was characterized as 3,4,2`,3`-tetrahydroxychalcone. Other important constituents were the chalcone isoliquiritigenin, the isoflavans (3S)-vestitol, (3S)-7-O-methylvestitol, the pterocarpan medicarpin, the phenylpropenes trans-anethol, methyl eugenol, elimicin, methoxyeugenol and cis-asarone, and the triterpenic alcohols lupeol and alpha- and beta- amyrins. The methanol extract exhibited high antioxidant activities by 2,2-diphenyl-1-picrylhydrazyl and beta-carotene/linoleic acid assay methods, and antimicrobial activity toward Gram-positive and Gram-negative bacteria. CONCLUSION: Structures are suggested for new substances never before seen in any kind of propolis. This is the first report of 3,4,2`,3`-tetrahydroxychalcone and a flavone C-glycoside in a propolis sample. (C) 2011 Society of Chemical Industry FAPESP CNPq |
Identificador |
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, v.91, n.13, p.2363-2370, 2011 0022-5142 http://producao.usp.br/handle/BDPI/27221 10.1002/jsfa.4468 |
Idioma(s) |
eng |
Publicador |
WILEY-BLACKWELL |
Relação |
Journal of the Science of Food and Agriculture |
Direitos |
restrictedAccess Copyright WILEY-BLACKWELL |
Palavras-Chave | #red propolis #isoflavonoids #phenylpropene derivatives #chalcones #Leguminosae #TANDEM MASS-SPECTROMETRY #CUBAN PROPOLIS #PHENOLIC COMPOSITION #CONSTITUENTS #ORIGIN #ANTIBACTERIAL #FLAVONOIDS #ISOFLAVONOIDS #EXTRACT #ANALOGS #Agriculture, Multidisciplinary #Chemistry, Applied #Food Science & Technology |
Tipo |
article original article publishedVersion |