Resonancia magnética cardiaca: medidas lineales y volumétricas en adultos sanos


Autoria(s): Heredia Sánchez, Fabian Mauricio; Cabezas, Andrés Mauricio
Contribuinte(s)

Trillos, Carlos

Data(s)

02/12/2015

Resumo

Introducción: La gran mayoría de las medidas de normalidad utilizadas para la interpretación de resonancia cardiaca son extrapoladas de las medidas de ecocardiografía. Los limitados registros de medidas de normalidad se encuentran ajustados en poblaciones extranjeras, no hay registros en latinoamericanos. Objetivo: Determinar las dimensiones cardiacas utilizando resonancia magnética en una población de personas sin antecedente médicos con repercusión cardiaca para lograr una muestra de valores que permitan ajustar las medidas de normalidad utilizadas por nuestro servicio. Materiales y métodos: se analizaron 45 sujetos sanos con edad comprendida entre los 21 y 45 años, las adquisiciones se realizaron utilizando un equipo de RM de 1,5 teslas, el análisis de las imágenes se realizó mediante el programa Cardiac Volume Vx. Se evaluaron múltiples parámetros morfofuncionales a través de análisis estadístico por medio del sistema SPSS versión 23. Resultados: Mediciones obtenidas de ventrículo izquierdo principales fueron volumen diastólico en mujeres de 62 ml +/- 7.1 y en hombres de 65 ml +/- 11.2 y fracción de eyección de 60 % +/- 5 en mujeres y de 62 % +/- 9 en hombres. En ventrículo derecho el volumen diastólico final se encontró 81.8 ml +/- 14.6 en mujeres y 100 ml +/- 24.8 en hombres y fracción de eyección de 53 % +/- 17 en mujeres y de 45 % +/- 12 en hombres. Volumen de fin de diástole de 50 +/- 12.7 ml en mujeres y de 49 ml +/- 19 ml en hombres y fracción de eyección de aurícula izquierda de 55 % +/- 0.08 en mujeres y de 50 % +/- 0.07 en hombres. Volumen de fin de diástole de 44.1 ml +/- 18.5 en mujeres y de 49.2 ml +/- 22.9 en hombres y fracción de eyección de aurícula derecha de 50 % +/- 11 en mujeres y de 45 % +/- 8 en hombres. Se obtuvieron otras medidas lineales y volumétricas adicionales de cavidades cardiacas y de grandes vasos supracardiacos. Conclusiones: se describen los valores de referencia de los parámetros morfofuncionales de las cavidades cardiacas y de vasos supracardiacos. El sexo fue tenido en cuenta como covariable relacionada con la modificación de los parámetros evaluados. Se sugieren variaciones en las medidas de cavidades cardiacas para la población estudiada relacionada con aclimatación crónica a la altitud de la ciudad de Bogotá.

Introduction: The vast majority of measures normally used for the interpretation of cardiac magnetic resonance are extrapolated measures echocardiography. Limited records of the normal measures are adjusted foreign populations, there are no records in Latin America. To determine the dimensions using cardiac magnetic resonance in a population of people without medical background with heart impact to achieve a sample set of values that allow normal measures used by our service. Methods: 45 healthy subjects aged between 21 and 45 years were analyzed, acquisitions were made using a team of RM 1.5 tesla, the image analysis was performed using the Cardiac Volume Vx program. Multiple morphological and functional parameters were evaluated by statistical analysis using the SPSS version 23 system. Results: Measurements obtained were major left ventricular diastolic volume in women aged 62 +/- 7.1 ml and 65 ml in men and 11.2 +/- ejection fraction of 60% +/- 5 women and 62% +/- 9 in men. Right ventricular end diastolic volume was 81.8 +/- 14.6 ml found in women and 100 +/- 24.8 ml in men and ejection fraction of 53% +/- 17 women and 45% +/- 12 men. End-diastolic volume of 50 +/- 12.7 ml in men and 49 ml +/- 19 ml in men and ejection fraction of left atrium of 55% +/- 0.08 in women and 0.07 in +/- 50% men. End-diastolic volume of 18.5 +/- 44.1 ml in women and 22.9 +/- 49.2 ml in men and ejection fraction of the right atrium of 50% +/- 11 women and 45% +/- 8 men . Additional linear and volumetric measurements of cardiac cavities and large vessels supracardiacos obtained. Conclusions: the reference values of the morphological and functional parameters of the heart chambers and vessels supracardiacos described. Sex was taken into account as a covariate associated with the modification of the parameters evaluated. Suggested changes in measures of cardiac cavities for the population studied related chronic altitude acclimatization Bogota.

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application/pdf

Identificador

http://repository.urosario.edu.co/handle/10336/11807

Idioma(s)

spa

Publicador

Facultad de medicina

Direitos

info:eu-repo/semantics/openAccess

Fonte

instname:Universidad del Rosario

reponame:Repositorio Institucional EdocUR

Poppe, Katrina. A meta-analysis of echocardiographic measurements of the left heart for the development of normative reference ranges in a large international cohort: the Echo NORMAL study. European Heart Journal – Cardiovascular Imaging, 2013.

Bellenger NG, Pennell DJ: Ventricular function. In Cardiovascular magnetic resonance. Edited by: Manning WJ, Pennell DJ. Churchill Livingstone, New York, USA; 2002.


Grothues F, Smith GC, Moon JCC, Bellenger NG, Collins P, Klein HU, Pennell DJ: Comparison of interstudy reproducibility of cardiovascular magnetic resonance with two-dimensional echocardiography in normal subjects and in patients with heart failure or left ventricular.

Salton C. Chuang M, Gender Differences and Normal Left Ventricular Anatomy in an Adult Population Free of Hypertension, Journal of the American College of Cardiology, 2002

Chaustre. Mendoza. L, Marti Bonmati L; Resonancia magnetica del ventrıculo izquierdo en sujetos sanos: valores normales de morfologıa, funcion, perfusion y viabilidad, Elsevier. 2009

Biswas S, Ananthasubramaniam K. Clinical utility of 3D echocardiography for the evaluation of ventricular function. Cardiology in Review. 2013; 21: 184-95.

Gutierrez-Chico JL, Zamorano JL, Perez de Isla L, Orejas M, Almerıa C, Rodrigo JL, et al. Comparison of left ventricular volumes and ejection fractions measured by three-dimensional echocardiography versus by two-dimensional echocardiography and cardiac magnetic resonance in patients with various cardiomyopathies. Am J Cardiol. 2005.

Kawel-boehm Nadine, Maceira A. Normal Values for Cardiovascular magnetic resonance in adults and children, Journal of Cardiovascular Magnetic Resonance – 2015

Hudsmith L. Petersen S. Normal human left and right ventricular and left atrial dimensions using steady state free precession magnetic resonance imaging, Journal of Cardiovascular Magnetic Resonance, 2005

Poppe K, A meta-analysis of echocardiographic measurements of the left heart for the development of normative reference ranges in a large international cohort: the EchoNoRMAL study, European Heart Journal – Cardiovascular Imaging (2014)

Lorenz CH, Walker ES, Morgan VL, et al. Normal human right and left ventricular mass, systolic function, and gender differences by cine magnetic resonance imaging. J Cardiovasc Magn Reson 1999.

Marcus JT, DeWaal LK, Gotte MJW, et al. MRI-derived left ventricular function parameters and mass in healthy young adults: relation with gender and body size. Int J Card Imaging 1999. 


Hendel R, Patel M. Appropriateness Criteria for Cardiac for Cardiac Computed Tomography and Cardiac Magnetic Resonance Imaging. Journal of the American College of Cardiology. Vol. 48, No. 7, 2006. Octubre 3, 2006: 000 – 000.

Melenovsky V, Borlaug BA, Rosen B, Hay I, Ferruci L, Morell CH, Lakatta EG, Najjar SS, Kass DA: Cardiovascular features of heart failure with preserved ejection fraction versus nonfailing hypertensive left ventricular hypertrophy in the urban Baltimore community: the role of atrial remodeling/dysfunction. J Am Coll Cardiol 2007, 49:198-207.

Dini FL, Cortigiani L, Baldini U, Boni A, Nuti R, Barsotti L, Micheli G: 
Prognostic value of left atrial enlargement in patients with idiopathic dilated cardiomyopathy and ischemic cardiomyopathy. Am J Cardiol 2002, 89:518-23.

Meris A, Amigoni M, Uno H, Thune JJ, Verma A, Kober L, Bourqoun M, McMurray JJ, Velazquez EJ, Maggioni AP, Ghali J, Arnold JM, Zelenkofske S, Pfeffer MA, Solomon SD: Left atrial remodelling in patients with myocardial infarction complicated by heart failure, left ventricular dysfunction, or both: the VALIANT Echo study. Eur Heart J 2009, 30:56-65.

Kizer JR, Bella JN, Palmieri V, Liu JE, Best LG, Lee ET, Roman MJ, Devereux RB: Left atrial diameter as an independent predictor of first clinical cardiovascular events in middle-aged and elderly adults: the Strong Heart Study (SHS). Am Heart J 2006, 151:412-8.

Nistri S, Olivotto I, Betocchi S, Losi MA, Valsecchi G, Pinamonti B, Conte MR, Casazza F, Galderisi M,Maron BJ, Cecchi F: on behalf of Participating Centers. Prognostic significance of left atrial size in patients with hypertrophic cardiomyopathy (from the Italian Registry for Hypertrophic Cardiomyopathy). Am J Cardiol 2006, 98:960-5.

Rossi A, Cicoira M, Florea VG, Golia G, Florea ND, Khan AA, Murray ST, Nguyen JT, O’Callaghan P, Anand IS, Coats A, Zardini P, Vassanelli C, Henein M: Chronic heart failure with preserved left ventricular ejection fraction: diagnostic and prognostic value of left atrial size. Int J Cardiol 2006, 110:386-92.

Oleaga L. Corazón: lo que el radiólogo debe conocer. En: Tardaguila Montero FM, Ferreiros Domınguez J, editors. Monografía SERAM. Imagen cardiovascular avanzada: RM y TC, Vol. 1. Madrid: Editorial Medica Panamericana; 2004.

Sandstede J, Lipke C, Beer M, Hofmann S, Pabst T, Kenn W, et al. Age- and gender-specific differences in left and right ventricular cardıac function and mass determined by cine magnetic resonance imaging. Eur Radiol. 2000; 10:438–42.

M. Maceira, 1 S. K. Prasad,1 M. Khan,2 and D. J. Pennell1. Normalized Left Ventricular Systolic and Diastolic Function by Steady State Free Precession Cardiovascular Magnetic Resonance. Journal of Cardiovascular Magnetic Resonance, 2006: 417 - 126.

Hudsmith LE, Petersen SE, Francis JM, Robson MD, Neubauer S. Normal human left and right ventricular and left atrial dimensions using steady state free precession magnetic resonance imaging. J Cardiovasc Magn Reson. 2005; 7:775–82.

Maceira AM, Cosin-Sales J, Roughton M, Prasad SK, Pennell DJ. Reference left atrial dimensions and volumes by steady state free precession cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2010; 12:65.

Wang Z, Reddy G, Gotway MB, et al. CT and MR imaging of pericardial disease. Radiographics. 2003; 23; S167-S180.

Biswas S, Ananthasubramaniam K. Clinical utility of 3D echocardiography for the evaluation of ventricular function. Cardiology in Review. 2013; 21: 184-95.

Losi MA, Nistri S, Galderisi M, et al. Echocardiography in patients with hypertrophic cardiomyopathy: usefulness of old and new techniques in the diagnosis and patho-physiological assessment. Cardiovasc Ultras. 2010.

Soman P, Swinburn J, Callister M, et al. Apical hypertrophic cardiomyopathy: bed-side diagnosis by intravenous contrast echocardiography. J Am Soc Echocardiogr. 2001.

Grothues F, Smith GC, Moon JCC, Bellenger NG, Collins P, Klein HU, Pennell DJ. Comparison of interstudy reproducibility of cardiovascular magnetic resonance with two-dimensional echocardiography in normal subjects and in patients with heart failure or left ventricular hypertrophy. Am J Cardiol 2002; 90:29–34.

Sievers B, Addo M, Breuckmann F, Barkhausen J, Erbel R. Reference right atrial function determined by steady-state free precession cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2007; 9:807–14.


Maceira AM, Cosin-Sales J, Roughton M, Prasad SK, Pennell DJ. Reference right atrial dimensions and volume estimation by steady state free precession cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2013; 15:29.

Kawel N, Turkbey EB, Carr JJ, Eng J, Gomes AS, Hundley WG, et al. Normal left ventricular myocardial thickness for middle-aged and older subjects with steady-state free precession cardiac magnetic resonance: the multi-ethnic study of atherosclerosis. Circ Cardiovasc Imaging. 2012; 5:500–8. 


Pennell DJ, Sechtem UP, Higgins CB, et al. European Society of Cardiology; Society for Cardiovascular Magnetic Resonance. Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report. J Cardiovasc Magn Reson 2004; 6:727–765

Boxt LM. Cardiac MR imaging a guide for the beginner. RadioGraphics 1999; 19:1009–1025; discussion.

Martin ET, Coman JA, Shellock FG, Pulling CC, Fair R, Jenkins K. Magnetic resonance imaging and cardiac pacemaker safety at 1.5-Tesla. J Am Coll Cardiol 2004; 7; 43:1315.

Nazarian S, Roguin A, Zviman MM, et al. Clinical utility and safety of a protocol for noncardiac and cardiac magnetic resonance imaging of patients with permanent pacemakers and implantable cardioverter defibrillators at 1.5 Tesla. Circulation 2006; 114:1277–1284

Reeder SB, Du YP, Lima JA, Bluemke DA. Advanced cardiac MR imaging of ischemic heart disease. RadioGraphics 2001; 21:1047–1074.

Kim HW, Klem I, Kim RJ. Detection of myocardial ischemia by stress perfusion cardiovascular magnetic resonance. Cardiol Clinics 2007; 25:57–70.

Saremi F, Grizzard JD, Kim RJ. Optimizing cardiac MR imaging: practical remedies for artifacts. RadioGraphics 2008; 28:1161–1187.

Miyazaki M, Lee VS. Nonenhanced MR angiography. Radiology 2008; 248:20–43.

Alfakih K, Plein S, Thiele H, Jones T, Ridgway JP, Sivananthan MU. Normal human left and right ventricular dimensions for MRI as assessed by turbo gradient echo and steady-state free precession imaging sequences. J Magn Reson Imaging. 2003;17:323–9. 


Hudsmith LE, Petersen SE, Francis JM, Robson MD, Neubauer S. Normal human left and right ventricular and left atrial dimensions using steady state free precession magnetic resonance imaging. J Cardiovasc Magn Reson. 2005; 7:775–82.

Maceira AM, Prasad SK, Khan M, Pennell DJ. Normalized left ventricular systolic and diastolic function by steady state free precession cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2006; 8:417–26. 


Sievers B, Kirchberg S, Bakan A, Franken U, Trappe HJ. Impact of papillary muscles in ventricular volume and ejection fraction assessment by cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2004; 6:9–16.

Winter MM, Bernink FJ, Groenink M, Bouma BJ, van Dijk AP, Helbing WA, et al. Evaluating the systemic right ventricle by CMR: the importance of consistent and reproducible delineation of the cavity. J Cardiovasc Magn Reson. 2008; 10:40.


Sievers B, Kirchberg S, Franken U, Bakan A, Addo M, John-Puthenveettil B,
et al. Determination of normal gender-specific left atrial dimensions by cardiovascular magnetic resonance imaging. J Cardiovasc Magn Reson. 2005; 7:677–83.


Hudsmith LE, Petersen SE, Francis JM, Robson MD, Neubauer S. Normal human left and right ventricular and left atrial dimensions using steady state free precession magnetic resonance imaging. J Cardiovasc Magn Reson. 2005; 7:775–82. 


Maceira AM, Cosin-Sales J, Roughton M, Prasad SK, Pennell DJ. Reference left atrial dimensions and volumes by steady state free precession cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2010; 12:65.


Sievers B, Addo M, Breuckmann F, Barkhausen J, Erbel R. Reference right atrial function determined by steady-state free precession cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2007; 9:807–14.


Maceira AM, Cosin-Sales J, Roughton M, Prasad SK, Pennell DJ. Reference right atrial dimensions and volume estimation by steady state free precession cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2013; 15:29.

Kawel N, Turkbey EB, Carr JJ, Eng J, Gomes AS, Hundley WG, et al. Normal left ventricular myocardial thickness for middle-aged and older subjects with steady-state free precession cardiac magnetic resonance: the multi-ethnic study of atherosclerosis. Circ Cardiovasc Imaging. 2012; 5:500–8.

Dawson DK, Maceira AM, Raj VJ, Graham C, Pennell DJ, Kilner PJ. Regional thicknesses and thickening of compacted and trabeculated myocardial layers of the normal left ventricle studied by cardiovascular magnetic resonance. Circ Cardiovasc Imaging. 2011; 4:139–46. 


Turkbey EB, Jain A, Johnson C, Redheuil A, Arai AE, Gomes AS, et al. Determinants and normal values of ascending aortic diameter by age, gender, and race/ethnicity in the Multi-Ethnic Study of Atherosclerosis (MESA). J Magn Reson Imaging. 2014; 39:360–8.

Davis AE, Lewandowski AJ, Holloway CJ, Ntusi NA, Banerjee R, Nethononda R, et al. Observational study of regional aortic size referenced to body size: production of a cardiovascular magnetic resonance nomogram. J Cardiovasc Magn Reson. 2014; 16:9.

Burman ED, Keegan J, Kilner PJ. Aortic root measurement by cardiovascular magnetic resonance: specification of planes and lines of measurement and corresponding normal values. Circ Cardiovasc Imaging. 2008; 1:104–13.

Pennell, D. J., Sechtem, U. P., Higgins, C. B., Manning, W. J., Pohost, G. M., Rademakers, F. E.,Yucel, E. K. (2004). Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report. European heart journal, 25(21), 1940-1965.

Grothues, F., Moon, J. C., Bellenger, N. G., Smith, G. S., Klein, H. U., & Pennell, D. J. (2004). Interstudy reproducibility of right ventricular volumes, function, and mass with cardiovascular magnetic resonance. American heart journal, 147(2), 218-223.

Lorenz, C. H., Walker, E. S., Morgan, V. L., Klein, S. S., & Graham, T. P. (1999). Normal human right and left ventricular mass, systolic function, and gender differences by cine magnetic resonance imaging. Journal of Cardiovascular Magnetic Resonance, 1(1), 7-21.

Souto Bayarri, M., García Tahoces, P., Masip Capdevila, L. R., Suárez Cuenca, J. J., Martínez Monzonís, A., & Vidal Carreira, J. J. (2011). Cuantificación semiautomática de la función ventricular izquierda y derecha en resonancia magnética cardíaca. Estudio preliminar. Radiología, 53(1), 39-46.

Caudron J, Fares J, Bauer F, et al. Evaluation of left ventricular diastolic function with cardiac MR imaging. Radiographics 2011; 31: 239-261.

GE Healthcare. 510 K. Notificación previa a la comercialización. Diciembre 11, 2012.

Minguez A. Sistema respiratorio y altura. Actividad física y enfermedades respiratorias. Revista digital. 2001. Año 7 – No 42.

TEME

Palavras-Chave #Epidemiología #Diagnóstico por imágenes #614.4 #Ecocardiografía #Cardiopatías #Cardiac MRI, Cardiac resonance, expected ranges, lineal and volumetric measurements.
Tipo

info:eu-repo/semantics/bachelorThesis

info:eu-repo/semantics/acceptedVersion