Eficacia de la limpieza corporal con clorhexidina en prevenir la sepsis neonatal en cuidado intensivo revisión sistemática
| Contribuinte(s) |
Morón Duarte, Lina Sofía |
|---|---|
| Data(s) |
25/05/2015
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| Resumo |
ANTECEDENTES. La mortalidad neonatal se debe principalmente a procesos infecciosos y a prematurez. Se ha sugerido que el lavado corporal total con clorhexidina podría reducir la mortalidad neonatal relacionada con infección. No existen revisiones sistemáticas que exploren la eficacia de esta intervención. Objetivo. Evaluar la eficacia y seguridad de la limpieza corporal total con clorhexidina en la prevención de las infecciones asociadas al cuidado de la salud en neonatos de alto riesgo hospitalizados en cuidado intensivo neonatal. Metodología. Se realizó una revisión sistemática de la literatura. La búsqueda se hizo a través de las bases de datos Medline, Embase, LilaCS, Cochrane library y el registro de ensayos clínicos del Instituto Nacional de Salud de Estados Unidos. Se incluyeron ensayos clínicos publicados en los últimos 15 años hasta el 30 de enero del 2015. Las variables cualitativas se estimaron mediante OR o RR con sus IC95%. Las variables cuantitativas mediante diferencias de promedios o diferencias estandarizadas de promedios con sus IC95%. Resultados: Se incluyeron 3 estudios en el análisis cualitativo y cuantitativo. No se encontró evidencia concluyente que permita recomendar el uso de la limpieza corporal total con clorhexidina en los recién nacidos hospitalizados en cuidado intensivo neonatal. Conclusión: No existe evidencia que permita concluir que la limpieza corporal total con clorhexidina al 0.25% es mejor respecto a otras intervenciones en la prevención de sepsis neonatal asociada al cuidado de la salud . Es una intervención segura sin efectos adversos significativos. Background: Neonatal mortality is mainly due to infectious processes and prematurity. It has been suggested that whole body washing with chlorhexidine could reduce neonatal mortality associated with infection. No systematic reviews that allow exploring the efficacy of this intervention. Objective:To evaluate the efficacy and safety of total body cleansing with chlorhexidine in preventing infections related with health care in high risk neonates hospitalized in intensive care units. Methodology:A systematic review of the literature was performed. The search was performed trough Medline , Embase , Lilacs , Cochrane library databases and registration of clinical trials at the National Institute of Health. We included clinical trials published in the last 15 years until January 30 , 2015. Qualitative variables were estimated by OR or RR with 95% CI. Quantitative variables by mean differences or standardized mean differences with 95% CI . Results: Three studies were included in the qualitative and quantitative analysis. No conclusive evidence to recommend the use of total body cleansing with chlorhexidine in infants hospitalized in neonatal intensive care was found. Conclusión: There is no evidence to conclude that the total body washing with chlorhexidine to 0.25% is better compared to other interventions in the prevention of infections associated with health care of high risk neonatal patient hospitalized in neonatal intensive care. It is a safe procedure without significant adverse effects. |
| Formato |
application/pdf |
| Identificador | |
| Idioma(s) |
spa |
| Publicador |
Facultad de medicina |
| Direitos |
info:eu-repo/semantics/openAccess |
| Fonte |
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| Palavras-Chave | #618.9201 #Neonatología #Clorhexidina #Sepsis neonatal #(MeSH): Chlorhexidine , neonatal sepsis , infection related to health care. |
| Tipo |
info:eu-repo/semantics/bachelorThesis info:eu-repo/semantics/acceptedVersion |
