Strain longitudinal global para la detección de estenosis coronaria significativa en pacientes con infarto agudo del miocardio


Autoria(s): Acosta, Rafael
Contribuinte(s)

Salazar, Gabriel

Data(s)

26/02/2015

Resumo

Introducción: La evaluación de la función miocárdica global y regional juega una papel crítico en el diagnóstico y manejo de los pacientes con enfermedad coronaria con importantes implicaciones pronosticas, las nuevas técnicas ecocardiográficas como la evaluación del STRAIN han sido validadas como una herramienta objetiva, comprehensiva y precisa para evaluar dichos parámetros. Objetivo: Determinar la capacidad del strain global longitudinal para la detección de estenosis coronaria significativa, número de territorios comprometidos y territorio anatómico del vaso culpable; en pacientes sin antecedentes de enfermedad coronaria previa con infarto agudo del miocardio. Diseño: estudio de pruebas diagnósticas retrospectivo en el que se utilizó como gold estándar la angiografía coronaria, se seleccionaron 64 pacientes con ecocardiograma transtorácico previo a la angiografía coronaria. Resultados: Se demostró una exactitud intermedia del strain global longitudinal para detectar estenosis coronaria por análisis de curvas ROC, con un área bajo la curva de 0,78 p= 0,000 (IC 0,6; 1,0), Una sensibilidad de 96.5% (91.7%, 101.3%), especificidad 40.0% (9.6%, 70.4%) y una prevalencia real del enfermedad coronaria de 85.1% (76.5%, 93.6%) Conclusiones: La medición de la función global y regional por medio del strain global longitudinal identifica pacientes con infarto agudo del miocardio que tienen estenosis coronaria significativa, número de territorios afectados, y la distribución anatómica de los posibles vasos culpables, sin embargo hay que tener precaución en su uso que sólo se limite a escenarios en donde pueda ser interpretado adecuadamente. Palabras clave: strain global bidimensional, detección de estenosis coronaria significativa, infarto del miocardio.

Introduction : Evaluation of global and regional myocardial function Playing a critical role in the diagnosis and management of patients with coronary artery disease with important prognostic implications , new echocardiographic techniques such as assessment and GLOBAL STRAIN have been validated as a tool objective , comprehensive and accurate to evaluate these parameters. Objective: Determine the capacity of global longitudinal strain for the detection of significant coronary stenosis, number of involved territories and anatomical territory of the culprit vessel; in patients with no history of coronary disease with acute myocardial infarction. Design: Retrospective study of diagnostic tests in which was used as gold standard coronary angiography, 64 patients were selected and took an echocardiography previous to coronary angiography. Results: an intermediate accuracy of global longitudinal strain was demonstrated to detect coronary stenosis by ROC curve analysis , with an area under the curve of 0.78 p = 0.000 (CI 0.6 , 1.0 ), a sensitivity of 96.5 % ( 91.7 % , 101.3 % ) , Specificity 40.0% ( 9.6 % , 70.4% ) and an actual prevalence of coronary artery disease of 85.1 % ( 76.5 % , 93.6 % ) Conclusions: The measurement of global and regional function by means of global longitudinal strain identifies patients with acute myocardial infarction who have significant coronary stenosis also discriminates the number of affected territories, and the anatomical distribution of possible vessels guilty, however should be careful in his use, using it only limited scenarios where it can be interpreted properly

Formato

application/pdf

Identificador

http://repository.urosario.edu.co/handle/10336/10305

Idioma(s)

spa

Publicador

Facultad de medicina

Direitos

info:eu-repo/semantics/openAccess

Fonte

instname:Universidad del Rosario

reponame:Repositorio Institucional EdocUR

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TEME

Palavras-Chave #616.1237 #Diagnóstico por imágenes #Cardiología #Strain longitudinal global #Estenosis coronaria significativa #Infarto agudo del miocardio #two-dimensional global longitudinal strainl, detection of significant coronary stenosis, myocardial infarction.
Tipo

info:eu-repo/semantics/bachelorThesis

info:eu-repo/semantics/acceptedVersion