Alteraciones respiratorias durante el sueño en niños con Síndrome Down a la altura de Bogotá


Autoria(s): Pinzón Gómez, Ginna Cecilia
Contribuinte(s)

Dueñas, Elida

Morón, Lina

Data(s)

11/06/2013

31/12/1969

Resumo

Objetivo: determinar la frecuencia de las diferentes alteraciones respiratorias durante el sueño (ARS) e hipertensión pulmonar (HTP) y establecer la saturación de oxígeno (SpO2) en vigilia, sueño y durante los eventos en niños con Síndrome Down (SD) a la altura de Bogotá (2640m) de acuerdo a grupos de edad e IMC. Métodos: estudio descriptivo de corte transversal, se incluyeron todos los niños con SD con sospecha de ARS remitidos a polisonograma (PSG) de octubre de 2011 a enero de 2013 a la Fundación Neumológica Colombina (FNC). Se dividieron en 3 grupos: apnea obstructiva, apnea obstructiva y central, sin apneas. Resultados: 74 niños, el 36,5% mujeres, edad media 4 años. 47,3% presento apnea obstructiva, más frecuente en >2 años, 35,1% apnea obstructiva y central, más frecuente en < 2 años y 17,6 % sin apnea. SpO2 promedio en apnea obstructiva 84,63%, apnea obstructiva y central: 81,8% y sin apnea: 86,85% (p 0,058). 23% presento obesidad, 16% con apnea obstructiva. 53 pacientes tenían ecocardiograma: 28% HTP, 53,3% tuvo apnea obstructiva y 26,7 apnea obstructiva y central, no diferencias significativas. SpO2 promedio en HTP 88,3% vigilia, 86,2% sueño REM, 85,7 % sueño no REM, no diferencia significativa comparada con pacientes sin HTP. Conclusiones: Las ARS son frecuentes en los niños con SD, La desaturación está presente en los niños con SD independiente del tipo de apnea. A todos los niños SD se les debe practicar un PSG en el primer año de vida.

Objective: To determine the frequency of sleep apnea syndromes (SAS) and pulmonary hypertension (PHT) and set the oxygen saturation (SpO2) during wakefulness, sleep and events in children with Down syndrome (DS) living in Bogota (2640m) according to age groups and BMI. Methods: Descriptive cross sectional study, we included all children with DS referred to Fundación Neumológica Colombiana to make a polysomnogram (PSG) between October 2011 and January 2013. They were divided into 3 groups: obstructive sleep apnea, central and obstructive apnea, without apnea. Results: 74 children, 36.5% women, mean age 4 years. 47.3% showed obstructive apnea, more common in > 2 years, 35.1% central and obstructive apnea more common in <2 years, and 17.6% without apnea. Average SpO2 in obstructive apnea 84.63%, central and obstructive apnea: 81.8% without apnea: 86.85% (p 0.058). 23% showed obesity, 16% with obstructive apnea. 53 patients had echocardiography: PHT 28%, 53.3% obstructive apnea and 26.7% central and obstructive apnea, no significant differences. Average SpO2 in PHT 88.3% wake, 86.2% REM sleep, 85.7% non-REM sleep, no significant difference compared with patients without PHT. Conclusions: SAS are common in children with DS; desaturation is present in children with DS independent of the kind of sleep apnea. All DS children should have a PSG in the first year of life.

Formato

application/pdf

Identificador

http://repository.urosario.edu.co/handle/10336/4461

Idioma(s)

spa

Publicador

Facultad de medicina

Direitos

info:eu-repo/semantics/embargoedAccess

Fonte

reponame:Repositorio Institucional EdocUR

instname:Universidad del Rosario

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Palavras-Chave #HIPERTENSIÓN PULMONAR #SÍNDROME DE DOWN #SÍNDROMES DE LA APNEA DEL SUEÑO - ETIOLOGÍA #Sleep Apnea Syndromes #Down Syndrome #Pulmonary Hypertension
Tipo

info:eu-repo/semantics/bachelorThesis

info:eu-repo/semantics/submittedVersion