Comparación de CPRE temprana y tardia en pacientes con pancreatitis aguda severa de origen biliar


Autoria(s): Carrion Lopez, Pedro Luis
Contribuinte(s)

Isaza-Restrepo, Andres

Vargas Barato, Felipe

Data(s)

14/12/2012

Resumo

INTRODUCCION: La obstrucción biliar es la principal causa de pancreatitis aguda y su curso es moderado a leve aunque un 20% desarrollan formas severas. La remoción de los cálculos por CPRE se ha empleado como terapéutica aunque su rol es controversial y no se ha demostrado su utilidad en forma temprana. El propósito de este estudio es observar la evolución de los pacientes con PASB en quienes se realice CPRE con respecto al curso de la enfermedad. METODOLOGIA: Estudio retrospectivo observacional descriptivo en pacientes con PASB llevados a CPRE. Entre junio y octubre de 2012 se encontraron 72 pacientes con PASB y patrón biliar obstructivo, 49 (68.06%) en los cuales se realizo de forma temprana (antes de 72 horas) y 23 (31,94 %) de forma tardía (después de las 72 horas). RESULTADOS: No se encontraron diferencias en la morbilidad entre los dos grupos observados. Se encontró una mayor incidencia de PASB en mujeres, no hubo complicaciones asociadas al procedimiento y no hubo mortalidad asociada en ninguno de los grupos. DISCUSION: El estudio no muestra que la realización de CPRE tardía influya de forma desfavorable en los pacientes con PASB. Se encontró mayor incidencia de PASB en mujeres y edad media de 61 años. Deben realizarse mas estudios como el presente con un mayor número de pacientes para demostrar que no hay aumento en la morbimortalidad en los pacientes que sean llevados a CPRE después de 72 horas de inicio de los síntomas y poder generar recomendaciones de manejo locales.

INTRODUCTION: Biliary obstruction is the leading cause of acute pancreatitis and its course is moderate to mild but 20% develop severe. The removal of stones by ERCP been used as therapeutic although its role is controversial and has not proved useful in early. The purpose of this study is to observe the evolution of patients with PASB in ERCP perform those regarding the course of the disease. METHODOLOGY: Retrospective observational study in patients with PASB descriptive carried ERCP. Between June and October 2012 we found 72 patients with biliary PASB and pattern obstruction, 49 (68.06%) which was held in early (before 72 pm) and 23 (31.94%) late (after 72 hours). RESULTS: No differences in morbidity between the two groups observed. It found a higher incidence of PASB in women, there were no complications associated with procedure and no mortality was observed in either group. DISCUSSION: The study shows that late ERCP an unfavorable influence PASB in patients. We found a higher incidence of PASB in women and mean age of 61 years. More studies like this with a larger number of patients to show no increase in morbidity and mortality in patients who are brought to ERCP after 72 hours of onset of symptoms and to generate local management recommendations.

Formato

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Identificador

http://repository.urosario.edu.co/handle/10336/4142

Idioma(s)

spa

Publicador

Facultad de Medicina

Direitos

info:eu-repo/semantics/closedAccess

Fonte

instname:Universidad del Rosario

reponame:Repositorio Institucional EdocUR

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TEME 0112 2012

Palavras-Chave #CONDUCTOS BILIARES - RADIOGRAFÍAS - UTILIZACIÓN #ENFERMEDADES DE LOS CONDUCTOS BILIARES - INVESTIGACIONES #HEPATOLOGÍA - INVESTIGACIONES #PANCREATITIS - INVESTIGACIONES #COLANGIOGRAFÍA RETROGRADA ENDOSCÓPICA (CPRE) - UTILIZACIÓN #ACUTE PANCREATITIS #endoscopic retrograde cholangiography #ERCP
Tipo

info:eu-repo/semantics/bachelorThesis

info:eu-repo/semantics/acceptedVersion