Comparación de la severidad y extensión de la enfermedad coronaria multivaso por Syntax Score en una poblaciòn de las Antillas Holandesas vs controles nacionales


Autoria(s): Medina Lòpez, Libardo Augusto; Gil Aldana, Victor José
Contribuinte(s)

Echeverri Arcila, Dario

Data(s)

01/04/2012

Resumo

En la Enfermedad Coronaria (EC) existen factores genéticos, socioculturales, medioambientales y raciales adicionales a los factores de riesgo cardiovascular mayores que podrían influir en su presentación. Se desconoce el impacto de la raza en la severidad de la enfermedad coronaria en los pacientes extranjeros que son enviados a nuestro Servicio. Objetivos: Comparar la severidad de la EC multivaso en una población de pacientes de las Antillas y Nacionales, pareados por la escala Framingham. Metodología: Realizamos un estudio de corte transversal, comparando pacientes colombianos contra pacientes provenientes de las Antillas holandesas con similares factores de riesgo según escala de Framingham, catalogándolos por grupos de riesgo bajo, intermedio, alto y muy alto. Todos con EC severa multivaso documentada por angiografía coronaria desde enero del 2009 hasta Junio de 2011. Se excluyeron pacientes con antecedentes de intervención percutánea o quirúrgica previa. Resultados: Ingresaron 115 pacientes internacionales y 115 pacientes nacionales. La relación hombres/mujeres 3:1. La proporción de grupos de riesgo fue de bajo riesgo 2.5%, intermedio 15%, alto 19.3%, y muy alto 63.4%. El Syntax Score en pacientes nacionales fue 14.3+/-7.4 y en internacionales 22.2+/-10.5 p: 0.002. Conclusiones: En pacientes provenientes de las Antillas Holandesas, valorados en nuestra institución, se observó una mayor severidad de la enfermedad coronaria comparada con una población nacional con factores de riesgo similares. Estos hallazgos sugieren la influencia de la raza y factores genéticos en la severidad y extensión de la EC

Coronary artery disease (CAD) is still the first cause of morbidity and mortality in the general population. CAD has genetic, social, cultural, environmental and race backgroundsbesides the traditional major risks factors. It is unknown the impact of race in CAD´s severity within patients from Netherland Antilles, frequently referred to our service. Purpose:To compare the severity and extension of multivessel coronary artery disease by SYNTAX score between patients from Netherland Antilles vs Colombian patients after matching by Framingham Score Materials and Methods: We carried out a transversal cross sectional study by comparing patients from the Netherland Antilles vs Colombian patients after matching by Framingham Score in four categories (low risk, intermediate risk, high risk and very high risk). The patients correspond to those having multivessel coronary artery disease diagnosed by coronary angiography between January 2009 to June 2011. Results: 115 Colombian patients and 115 patients coming from the Netherland Antilles were included in this study, in a 3:1 ratio between females and males.. The proportion of patients belonging to several groups of risk where as follows: 2.5% low risk, 15% intermediate risk, 19.3% high risk, and 63.4% very high risk. The Syntax score for coronary artery disease was significantly higher among Caribbean from the Netherland Antilles (22.2+/-10.5) than among Colombians (14.3+/-7.4) p: 0.002. Conclusions: Patients coming from the Netherland Antilles had a higher severity index for coronary disease measured by angiography, after controlling for recognized risk factors. These findings support the notion that coronary disease is influenced by race, and genetic backgrounds. This finding is important for policies making in our service, a referral place for international patients.

Formato

application/pdf

Identificador

http://repository.urosario.edu.co/handle/10336/3617

Idioma(s)

spa

Publicador

Facultad de Medicina

Direitos

info:eu-repo/semantics/openAccess

Fonte

instname:Universidad del Rosario

reponame:Repositorio Institucional EdocUR

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TEME 0058 2012

Palavras-Chave #ENFERMEDAD CORONARIA - INVESTIGACIONES - ESTUDIO DE CASOS #TRAUMATISMOS CARDIACOS - INVESTIGACIONES - ESTUDIO DE CASOS #CARDIOLOGIA - INVESTIGACIONES - ESTUDIO DE CASOS #Coronary artery disease #Score Syntax
Tipo

info:eu-repo/semantics/bachelorThesis

info:eu-repo/semantics/acceptedVersion