Impact of international consensus guidelines on antiviral therapy of chronic hepatitis C patients in Switzerland.


Autoria(s): Overbeck, K.; Dufour, J.F.; Müllhaupt, B.; Helbling, B.; Borovicka, J.; Malinverni, R.; Heim, M.; Moradpur, D.; Cerny, A.; Rickenbach, M.; Negro, F.
Data(s)

2010

Resumo

To assess the impact of international consensus conference guidelines on the attitude of Swiss specialists when facing the decision to treat chronic hepatitis C patients. Questionnaires focusing on the personal situation and treatment decisions were mailed to 165 patients who were newly diagnosed with hepatitis C virus (HCV) infection and enrolled into the Swiss Hepatitis C Cohort Study during the years 2002-2004. Survey respondents (n = 86, 52.1%) were comparable to non-respondents with respect to severity of liver disease, history of substance abuse and psychiatric co-morbidities. Seventy percent of survey respondents reported having been offered antiviral treatment. Patients deferred from treatment had less advanced liver fibrosis, were more frequently infected with HCV genotypes 1 or 4 and presented more often with a history of depression. There were no differences regarding age, socio-economic background, alcohol abuse, intravenous drug abuse or methadone treatment when compared with patients to whom treatment was proposed. Ninety percent of eligible patients agreed to undergo treatment. Overall, 54.6% of respondents and 78.3% of those considered eligible had actually received antiviral therapy by 2007. Ninety-five percent of patients reported high satisfaction with their own hepatitis C management. Consistent with latest international consensus guidelines, patients enrolled in the Swiss Hepatitis C Cohort with a history of substance abuse were not withheld antiviral treatment. A multidisciplinary approach is warranted to provide antiviral treatment to patients suffering from depression.

Identificador

https://serval.unil.ch/notice/serval:BIB_2135E12296F8

info:pmid:20131123

https://serval.unil.ch/resource/serval:BIB_2135E12296F8.P001/REF

http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_2135E12296F86

urn:nbn:ch:serval-BIB_2135E12296F86

Idioma(s)

eng

Fonte

Swiss medical weekly1409-10146-152

Palavras-Chave #Hepatitis C Virus; Hepatitis C Treatment; Barriers To Treatment; Treatment Decision-Making; Consensus Guidelines; Virus-Infection; Interferon-Alpha; Plus Ribavirin; Veterans; Predictors; Disorders; Medicine; Illness; Article; Care
Tipo

info:eu-repo/semantics/article

article

Formato

application/pdf

Direitos

info:eu-repo/semantics/openAccess

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