Mixed chimaerism; detection and significance following BMT


Autoria(s): McCann, S R; Lawler, M; Lawler, Mark
Data(s)

01/02/1993

Resumo

<p>Residual recipient haematopoietic cells may coexist with donor haemopoietic tissue following BMT. This is known as mixed chimaerism. The incidence of mixed chimaerism varies with the sensitivity of the detection system used; DNA based methodologies are the most sensitive. The influence of mixed chimaerism on leukaemia relapse and graft rejection is unclear. The lineages in which mixed chimaerism occurs may affect outcome.</p>

Identificador

http://pure.qub.ac.uk/portal/en/publications/mixed-chimaerism-detection-and-significance-following-bmt(0c8e2cd2-cfd2-4d82-8fde-9b2b5e24a625).html

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

McCann , S R , Lawler , M & Lawler , M 1993 , ' Mixed chimaerism; detection and significance following BMT ' Bone Marrow Transplantation , vol 11 , no. 2 , pp. 91-4 .

Palavras-Chave #Anemia, Aplastic #Bone Marrow Purging #Bone Marrow Transplantation #Chimera #Graft Survival #Hematopoietic Stem Cells #Humans #Leukemia #Neoplastic Stem Cells
Tipo

article